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127005 trials found · Page 5468 of 6351
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Can exercise tame hunger hormones? new study investigates
Knowledge-focused CompletedThis study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin sensitivity, obesity, and vascular function.
Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:52 UTC
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Ear freezing therapy tested for insomnia – does it work?
Symptom relief CompletedThe aim of the study is to show that auriculotherapy is effective in the treatment of chronic insomnia.
Sponsor: Hopital Foch • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Steady drip vs. shots: which helps heart surgery patients wake up faster?
Symptom relief CompletedRandomized single blind controlled clinical trial to test the benefit of sufentanil infusion over bolus dosing to reduce time to extubation and reduced length of ICU stay.
Phase 4 • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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New implant-free surgery shows promise for shoulder instability
Disease control CompletedThe purpose of this study is to evaluate the clinical and radiographic results after surgical treatment with implant-free allograft in the treatment of Anterior Shoulder Dislocation and to assess the safety of the surgery.
Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Lupus patients enrolled in major Long-Term observation study
Knowledge-focused Recruiting nowSystemic lupus erythematosus is a complex systemicautoimmune disease that can affect most organs of the human body. Although they are many recommendations on the diagnosis and managment of SLE, diagnosis and therapeutic managment is still challenging. A pluridisciplinary consul…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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New app helps breast cancer patients see their future after reconstruction
Knowledge-focused OngoingThis clinical trial evaluates whether a decision aid application (app) is effective in helping breast reconstruction surgery patients make informed decisions about breast reconstruction surgery. Researchers have created a computer app for breast reconstruction surgery patients th…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Frozen shoulder study: dry needling put to the test
Symptom relief Stopped earlyThis study evaluates the addition of dry needling to exercise as part of physical therapy for the treatment of shoulder adhesive capsulitis. There will be two groups. One will receive actual dry needling to the clinically determined shoulder / parascapular trigger points. The oth…
Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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New study aims to uncover hidden liver risks of immunotherapy
Knowledge-focused Recruiting nowIn this multi-center prospective observational study, the investigators plan to identify the incidence and risk factors for checkpoint inhibitor-induced liver injury and characterize biochemical, genetic, immunological, and histological features associated with it.
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Taiwan study monitors MS drug fingolimod for side effects
Disease control Recruiting nowThe purpose of the study is to describe the safety profile of fingolimod in the Taiwanese multiple sclerosis population. This study aims to collect the safety data in patients newly initiated on fingolimod for one year.
Phase 4 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Cancer's hidden toll: study probes social struggles of young patients
Knowledge-focused OngoingParticipants are being asked to take part in this clinical trial, a type of research study, because investigators want to learn more about the social experiences adolescents and young adults who are being treated or have been treated for cancer. Primary Objectives * Describe di…
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Blood samples could unlock secrets of rare brain diseases
Knowledge-focused Recruiting nowThe aim of this project is to improve biological collections of patients presenting rare neurological disorders with known or suspected autoimmune origin. This collection will provide appropriate biological samples to identify new biomarkers and to be accessible to the medical, s…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Heart fat linked to pump problems in common heart failure
Knowledge-focused CompletedHeart failure with preserved ejection fraction (HFpEF) refers to a group of symptoms and signs of heart failure, normal or near-normal left ventricular systolic function (EF\>50%), and ventricular muscle diastolic dysfunction and A clinical syndrome characterized by decreased com…
Sponsor: Dongying Zhang • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Can a new training module make future doctors better at discussing gun safety?
Knowledge-focused OngoingIn the United States, nearly one in every three households contains at least one firearm, and roughly 20-25% of American adults personally own a firearm. Such easy access to firearms is a major contributor to the uniquely high levels of firearm-related violent death in the United…
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Mayo clinic launches major study to uncover hidden fatty liver disease
Knowledge-focused Recruiting nowResearchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults with NAFLD and NASH to validate models of NAFLD diagnosis and determine long-term o…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Scientists launch major data hunt for rare bone diseases
Knowledge-focused Recruiting nowRD-DATA is a retrospective and prospective data collection, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains: personal information, clinical data, genetic…
Sponsor: Luca Sangiorgi • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Lavender and peppermint scents tested for chemo side effects
Symptom relief CompletedThe purpose of this research study is to determine whether using aromatherapy during chemotherapy infusion treatments in the outpatient Oncology setting promote relief of nausea and anxiety. The objectives of this study are: 1. To promote relief of nausea using peppermint aromat…
Sponsor: Central DuPage Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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New imaging tool could forecast pancreatic cancer survival
Knowledge-focused Recruiting nowPancreatic ductal adenocarcinoma (PDAC), representing 85-95% of pancreatic cancers, is a highly lethal malignancy with a dismal 5-year survival rate below 8%. Emerging evidence highlights the critical need for non-invasive imaging biomarkers to stratify prognosis and guide therap…
Sponsor: Yu Shi • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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New scope procedure aims to calm chronic pancreatitis pain
Symptom relief CompletedThe purpose of this study is to evaluate whether endoscopic ultrasound (EUS) only versus EUS + endoscopic retrograde cholangiopancreatography (ERCP) with pancreatic endotherapy reduces pain in the treatment of chronic pancreatitis with pancreatic duct obstruction.
Sponsor: Oregon Health and Science University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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2000 patients join effort to unravel mysteries of stomach and gut disorders
Knowledge-focused Recruiting nowFunctional digestive pathologies are defined by symptoms such as functional dyspepsia, gastroesophageal reflux, irritable bowel syndrome, gastroesophageal reflux, functional constipation, functional diarrhea, functional bloating, the opioid-induced constipation and fecal incontin…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Frozen shoulder breakthrough? injection combo shows promise in small study
Symptom relief CompletedThe purpose of this study is to identify clinical and MRI factors associated to a better response to arthrographic distension in patients with severe capsulitis.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 26, 2026 15:37 UTC