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116076 trials found · Page 5468 of 5804
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New eye lens aims to sharpen Mid-Range sight after cataracts
Disease control TerminatedA Prospective, Single-Center, Randomized Clinical Investigation to evaluate the safety and performance of the enVista® Aspire ™ (EA) intraocular lens (IOL) when compared to the MX60E monofocal IOL (control lens) and an IOL with a slightly extended depth of focus (active comparato…
Phase: NA • Sponsor: Bausch & Lomb Incorporated • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Liver impairment drug study completed: how golcadomide behaves
Knowledge-focused CompletedThe purpose of this study is to assess the drug levels and safety of golcadomide (BMS-986369) in adult participants with moderate and severe Hepatic Impairment (HI), and in matched healthy control participants with normal hepatic function.
Phase: PHASE1 • Sponsor: Celgene • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Eye-Tracking study reveals how cigar warnings grab attention
Knowledge-focused CompletedThe goal of this research is to determine how removal of little cigar and cigarillo (LCC) flavor descriptors on packaging impacts attention and affective responses to LCC warnings. A study will be conducted using eye tracking, electrodermal activity (galvanic skin response), and …
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Experimental clotting agent VMX-C001 tested with common blood thinners
Knowledge-focused CompletedA single centre, open-label study to assess the effects of VMX-C001 in combination with an oral FXa DOAC on the efficacy of Unfractionated Heparin (UFH) and of VMX-C001 alone on the efficacy of Low Molecular Weight Heparin (LMWH) in healthy subjects conducted in two parts: UFH c…
Phase: PHASE1 • Sponsor: VarmX B.V. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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AI-Powered bladder check speeds up pelvic ultrasound for teens
Diagnosis CompletedPoint-of-Care Ultrasound (POCUS) is a relatively quick and non-invasive technique to assess bladder fullness which will be provided under standard of care. The goal of this study is to assess for bladder fullness by measuring bladder volume using a handheld POCUS with AI technolo…
Phase: NA • Sponsor: Nicklaus Children's Hospital f/k/a Miami Children's Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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Beetroot rinse may alter oral microbiome, tiny study hints
Knowledge-focused CompletedThe study is aimed to determine if changes to the oral microbiome occur after the use of a nitrate rich mouth rinse. Participants with be asked to use either a controlled (water) mouthrinse once daily for 2 weeks while maintaining normal oral hygiene practices, or use the nitrate…
Phase: NA • Sponsor: Dalhousie University • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:01 UTC
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AI teaches anesthesia trainees to see hearts clearly
Knowledge-focused OngoingThis pilot study serves to assess the diagnostic adequacy of Artificial Intelligence (AI)-guided point-of-care. Focused echocardiography examinations will be obtained by Anesthesiology trainees and assessed by an expert Cardiologist Echocardiographer. AI-guided echocardiography e…
Sponsor: Loma Linda University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Healthy volunteers help uncover Vamorolone's enzyme effects
Knowledge-focused CompletedThe purpose of this study was to investigate how vamorolone affects the CYP3A4 enzyme in humans by measuring the pharmacokinetics of midazolam and its metabolite, 1'-hydroxymidazolam, in healthy subjects. The pharmacokinetics of midazolam were measured on Day 1 and then on Day 14…
Phase: PHASE1 • Sponsor: Santhera Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Texts and calls may help heart patients get healthy food
Knowledge-focused CompletedThe purpose of this research is to see if offering more navigation and text-message support will help increase participation and engagement in a Food is Medicine program. The study will recruit people currently participating in cardiac rehabilitation. People will be randomly assi…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Nurse turnover secrets revealed: generational study uncovers key factors
Knowledge-focused CompletedPurpose 1. To understand the current status of demographic characteristics, inclination to resign, Psychological Capital, work environment and job satisfaction, and political skills among incumbent clinical nursing staff across different generations. 2. To understand the correla…
Sponsor: Mackay Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Ballet class tested as therapy for Kids' twisted hips
Symptom relief CompletedThis study looks at how ballet training affects movement and personal feelings in children with a condition called idiopathic coxa antetorta.
Phase: NA • Sponsor: University Children's Hospital Basel • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Whitening toothpaste shows promise in stain removal study
Symptom relief CompletedThis randomized, examiner-blind, parallel-group clinical study evaluated the effectiveness of a whitening toothpaste compared with a control toothpaste in removing extrinsic tooth stain over six weeks of twice-daily unsupervised use. Adult subjects were assessed at baseline and a…
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New azithromycin gel shows promise in early absorption study
Knowledge-focused CompletedThis is an exploratory study to describe the pharmacokinetics of the azithromycin oral and rectal oleogel in humans compared to the reference oral drug to (Zithromax) assess the impact of the novel formulation on bioavailability. The investigators will perform a randomized, balan…
Phase: PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Gene therapy for krabbe disease: did it last?
Knowledge-focused TerminatedThis is an observational study that will enroll any patients with Krabbe disease that have participated in prior interventional clinical trials involving the administration of FBX-101.
Sponsor: Forge Biologics, Inc • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:47 UTC
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High-Tech mouthguard measures grinding force during sleep
Knowledge-focused TerminatedThe goal of this study is to determine if the Otis Brux-Sensor Night Guard (OBSNG) can record the bite compression forces of participants with Bruxism. The main questions it aims to answer is: 1. Is it possible to design and miniaturize electrical hardware components small enoug…
Sponsor: Otis Dental, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Thermal camera could take guesswork out of Kids' pain blocks
Knowledge-focused Recruiting nowThis study aims to evaluate the accuracy of temperature change (ΔT) measurements using infrared thermography to predict a successful erector spinae plane block in pediatric patients undergoing inguinal hernia repair under general anesthesia.
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:02 UTC
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Dental bone graft showdown: which material keeps your jaw stronger?
Knowledge-focused CompletedTooth extraction is among the most common dental treatments. The procedure results in the formation of a bone defect. During the healing phase, the vertical and horizontal diameters of the alveolar ridge decrease, which has a negative impact on planned prosthetic or implantoprost…
Phase: NA • Sponsor: Medical University of Silesia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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How many moms breastfeed exclusively at 3 months? new study investigates
Knowledge-focused CompletedEvaluate the prevalence of exclusive breastfeeding at M3 within the Martigues CH.
Sponsor: Centre Hospitalier de Martigues • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Fibromyalgia's hidden impact on sleep apnea revealed
Knowledge-focused CompletedObstructive type sleep apnea syndrome is a clinical condition characterized by apnea, hypopnea and oxygen desaturation due to narrowing of the upper airway during sleep. Obesity is considered a major predisposing factor for OSAS. In addition, various recent studies have reported …
Sponsor: Kirsehir Ahi Evran Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Timing of leucine supplements may boost muscle in seniors
Knowledge-focused Recruiting nowSarcopenia describes the progressive decline of muscle mass and strength with advancing age and is associated with increased frailty and morbidity, however we do not currently have an effective treatment. Protein feeding and exercise is known to increase muscle mass, but aged mus…
Phase: NA • Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC