Frozen shoulder breakthrough? injection combo shows promise in small study
NCT ID NCT04653636
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked at 55 adults with severe frozen shoulder (pain and stiffness for at least 3 months) who had not improved with standard treatments. They received one to three injections of steroid and numbing medicine into the shoulder joint, followed by intensive physiotherapy. The goal was to find out which patients respond best, based on MRI and clinical factors, with pain and function measured after one month.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
corticosteroid injection (betamethasone or triamcinolone hexacetonide) with lidocaine and saline
What this could lead to
If successful, this could help identify which patients with severe frozen shoulder benefit most from this injection-plus-physiotherapy approach, leading to more personalized treatment.
What could go wrong
This is a small, completed study (55 people) looking for predictive factors, not a large trial testing effectiveness. Results may not apply to all patients, and the procedure carries risks like infection or temporary pain increase.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis
Paris, IDF, 75014, France