Precision injection showdown: which spot stops frozen shoulder pain best?
NCT ID NCT07710651
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This trial tests two ways to deliver a steroid injection for adhesive capsulitis, or frozen shoulder — a condition that causes pain and stiffness. One method injects into the shoulder joint, the other into the tissue around it, both guided by ultrasound. Researchers want to see which approach better reduces pain and improves movement in daily life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- betamethasone combined with lidocaine, given as an ultrasound-guided injection
- What this could lead to
- If one technique proves superior, it could become the preferred standard for treating frozen shoulder, offering faster pain relief and better shoulder function.
- What could go wrong
- This is a small, early-stage trial with only 34 participants, so results may not apply to everyone. Steroid injections carry risks like infection or tendon damage, and the benefit may be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
34 people
The number who actually took part.
- Started
-
Aug 2023
- Finished
-
Mar 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: -Diagnosis of unilateral adhesive capsulitis, characterized by shoulder pain and restriction of both active and passive range of motion. Exclusion Criteria: * Secondary glenohumeral joint motion limitation due to inflammatory, degenerative, metabolic, or infectious arthritis. * History of cerebrovascular accident (stroke). * History of fracture involving the affected shoulder. * Presence of any neurological deficit affecting the upper extremity. * Previous surgery involving the affected shoulder. * History of shoulder trauma. * Pregnancy or breastfeeding. * Known hypersensitivity or allergic reaction to local anesthetics or corticosteroids used in the study. * Current use of anticoagulant therapy. * Active inflammatory or infectious disease. * Active psychiatric disorder. * Uncontrolled hypertension. * Uncontrolled diabetes mellitus. * Uncompensated chronic heart, liver, or renal failure. * Presence of vascular or malignant disease affecting the shoulder region.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Istanbul University- Cerrahpasa
Istanbul, Fatih, 34093, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Hormone therapy may thaw frozen shoulders faster — a trial puts it to the test
- Can a neck glide unlock a frozen shoulder?
- Can a specific mobilization technique unfreeze a frozen shoulder faster?
- Can a smartphone game help heal a frozen shoulder?
- Microembolization may outlast steroid shots for frozen shoulder