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127005 trials found · Page 5326 of 6351
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New pain block may cut opioid use after hernia surgery
Symptom relief OngoingWhile studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is particularly scarce. Therefore, we designed a prospective,…
Early phase 1 • Sponsor: Leslie Son • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Alaska school program teaches kids to avoid deadly shellfish toxins
Prevention CompletedThe purpose of this tribally co-led community-based participatory research in partnership with Sitka Tribe of Alaska was to help prevent Paralytic Shellfish Poisoning (PSP) in children of Southeast Alaska. The investigators assessed whether an education intervention led to change…
Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Jun 27, 2026 07:53 UTC
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Can a home blood pressure monitor keep new moms safe?
Knowledge-focused CompletedThe purpose of this research study is to find out the usefulness of checking a woman's blood pressure remotely (at home) for 3 weeks after being discharged from the hospital after having a baby (or babies). Some women can develop hypertension, or high blood pressure, after delive…
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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6,000 babies join study to unlock secrets of preterm development
Knowledge-focused OngoingThe purpose of this study is to conduct a long-term follow-up of preterm infants with different birth conditions, aiming to provide data and resources for future care and to identify predictive and influencing factors related to their functional development over time. It is hypot…
Sponsor: Chang Gung Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Blood biomarkers may help avoid unnecessary surgery in boys with testicle issues
Knowledge-focused CompletedBackground: Undescended testicles (UDTs) are common in male infants. Untreated UDT poses risks such as infertility (IF), testicular cancer (TC), and testicular torsion (TT). Retractile testicles (RTs) sporadically ascend from the scrotum. UDT requires early surgical correction, w…
Sponsor: Dr. Mevlüt Keleş • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Rice swap shows promise for prediabetes
Disease control CompletedPrediabetes is a condition where blood sugar levels are higher than normal but not yet high enough to be diagnosed as diabetes. Without lifestyle changes, people with prediabetes often develop type 2 diabetes, a serious disease affecting millions worldwide. Diet plays a crucial r…
Sponsor: Dr. Soetomo General Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Diet showdown: which eating plan calms IBS best?
Symptom relief By invitation onlyThe aim of the present study is to compare the efficiency of low FODMAP and SSRD to reduce symptoms in IBS, and to study the mechanisms and consequences of the two diets.
Sponsor: Region Skane • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Kids take the lead: new study lets children with disabilities choose their own therapy goals
Symptom relief Recruiting nowChildren with disabilities often access rehabilitation services to improve their abilities to participate in everyday activities. Goal-directed therapy is considered an important therapeutic strategy to achieve outcomes that are meaningful to families. Not a lot is known about th…
Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jul 17, 2026 00:00 UTC
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New study tracks pelvic fracture healing in seniors
Knowledge-focused OngoingProspective data will be collected in approximately 420 patients, above the age of 65, suffering from an FFP type fracture equal to or higher than type II, according to Rommens and Hofmann. Patients will be followed up according to the standard (routine) for up to 1 year after t…
Sponsor: AO Innovation Translation Center • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Which carpal tunnel surgery hurts less? study compares two techniques
Symptom relief CompletedWe are looking at whether there is a difference in pain and function in the very early period when comparing carpal tunnel release performed by the endoscopic technique versus the open technique.
Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Sweet science: honey may help fight insulin resistance
Disease control CompletedThe main objective of the study is to evaluate the effects of daily honey consumption on insulin resistance as a preventive measure against diabetes. in women with insulin resistance.
Sponsor: University of Jordan • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can cinnamon and education ease diabetic nerve pain?
Symptom relief CompletedThe purpose of this study was to assess the effects of a diabetes education intervention with cinnamon supplement on blood glucose, lipid profile, body mass index (BMI), and peripheral neuropathy pain in adults with type 2 diabetes. A quasi-experimental pretest/post-test design …
Sponsor: Al-Quds University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Smart foot scanner could keep heart failure patients out of hospital
Knowledge-focused CompletedThis study will aim to collect proof of concept data to inform the study design of a larger paired comparison study to establish key research questions about the Heartfelt device. The current study will be run with 2 parallel workstreams. Both are presented here: Data collected …
Sponsor: Heartfelt Technologies • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Could a short steroid course ease pain after knee surgery?
Symptom relief Recruiting nowThe purpose of this study is to evaluate the efficacy of an oral methylprednisolone taper on acute postoperative pain, function, opioid consumption, nausea, and complications following outpatient total knee arthroplasty (TKA). We hypothesize that administration of an oral methylp…
Phase 4 • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Hormone clues may unlock secrets of dangerous blood pressure
Knowledge-focused CompletedAcute severe hypertension is a common and heterogeneous clinical condition associated with significant short-term morbidity and health care utilization. Despite its frequency, underlying pathophysiological mechanisms remain poorly characterized, particularly regarding the role of…
Sponsor: School of Medicine. National University of Cuyo • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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New hip block cuts Post-Surgery painkiller use
Symptom relief CompletedThis study aims to evaluate the effect of ultrasound-guided pericapsular nerve group (PENG) block on postoperative tramadol consumption, pain scores, and clinical outcomes in patients undergoing partial hip prosthesis surgery. Patients aged 18-75 years scheduled for surgery under…
Sponsor: University of Gaziantep • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Warm water relief: showering during labor eases pain and anxiety
Symptom relief CompletedThis study examined whether showering during labor affects pain, anxiety, comfort, satisfaction, and labor outcomes in women undergoing vaginal birth. Non-pharmacological methods are commonly used to support women during labor, and warm showering may help reduce discomfort and em…
Sponsor: Nilgun Avci • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Moms' fat levels in pregnancy may shape Baby's body fat
Knowledge-focused Recruiting nowThis study plans to learn more about how triglyceride levels in pregnancy affect newborn fat mass. Obesity in pregnancy, in the absence of gestational diabetes, is now the most common cause of large-for-gestational-age infants and increased newborn fat mass. Previous data support…
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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3D printed insoles aim to prevent diabetic foot ulcers
Symptom relief CompletedIn this research study, the investigators are evaluating if novel custom foot orthotics improves foot health and mobility for people who are at increased risk of developing foot ulcers. The investigators are comparing different methods of custom foot orthotic fabrication in peopl…
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Scientists hunt for hidden genes behind common bleeding disorder
Knowledge-focused CompletedVon Willebrand disease (VWD) is caused by either quantitative or qualitative von Willebrand (VWF) defects and is the commonest inherited bleeding disorder with an estimated prevalence of about 1% in the general population. According to several guidelines, patients with a mild qua…
Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC