Scientists hunt for hidden genes behind common bleeding disorder
NCT ID NCT05116501
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study examined the DNA of 254 people to find genetic changes that might explain why some individuals have mildly low levels of von Willebrand factor, a protein important for blood clotting. Researchers used whole-exome sequencing to look for variants in known and new genes. The goal was to better understand the causes of this condition, which affects about 1% of the population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand the genetic causes of low VWF levels, potentially leading to improved diagnosis and personalized care for people with mild bleeding disorders.
- What could go wrong
- This is a completed observational study, not a treatment trial. It only looks for genetic links and does not test any therapy, so it cannot directly improve health or cure the condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, A.B.Bonomi Hemophilia and Thrombosis Center
Milan, Lombardy, 20122, Italy