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116076 trials found · Page 5171 of 5804
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Plastic bag trick may protect tiny babies from dangerous chills
Prevention CompletedParticular attention is paid to thermal management of preterm neonates in neonatal intensive care units because of the major risk of morbidity associated with hypothermia. Percutaneous central venous catheter placement is essential to ensure adequate caloric intake and intravenou…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Prevention
Last updated Jun 27, 2026 13:08 UTC
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97,000 women join study to see if new IUD prevents pregnancy as expected
Disease control OngoingThis study is designed to investigate whether LCS12 is associated with an increased risk of unintended pregnancy compared to Mirena and to copper IUDs. The objective is to assess among new users the risks of certain events (e.g. contraceptive failure rate, ectopic pregnancy, uter…
Sponsor: Center for Epidemiology and Health Research, Germany • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Scientists hunt for hidden causes of painful leg ulcers in sickle cell disease
Knowledge-focused CompletedBackground: \- People with sickle cell disease and other blood disorders sometimes get chronic leg ulcers. These are wounds that develop on the skin and don t go away. Current treatments do not work very well, so researchers want to learn more about why the ulcers happen. They w…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Large study looks at how a 25-Gene cancer test affects patients and families
Knowledge-focused CompletedThis study is about understanding the use of a genetic test (Myriad Genetics myRisk panel) that analyzes 25 genes related to different hereditary cancer conditions. The investigators hope to learn more about how this type of genetic test is used clinically. The investigators also…
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Which fibroid treatment is cheapest and safest? new study compares options
Disease control CompletedThis Post Market study is being conducted to compare the direct and indirect cost of three approaches (GFA, myomectomy, and uterine artery embolization) for the treatment of symptomatic uterine fibroids. In addition, data from this study is being used to satisfy the requirements …
Phase: NA • Sponsor: Acessa Health, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Decision aids may ease patient uncertainty in hand surgery
Knowledge-focused TerminatedThe investigators plan a prospective randomized controlled study that compares the treatment decisions made by patients who receive decision aids, as compared to patients treated with usual care and the American Society for Surgery of the Hand brochures. The investigators expect …
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Zapping the brain to stop the shakes: small trial shows promise
Symptom relief CompletedThe purpose of this study is to determine whether transcranial cathodal direct current stimulation (tDCS) delivered over the cerebellum can improve essential tremor.
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Simple blood test may spot hidden blood vessel damage in kids with growth issues
Knowledge-focused CompletedPrincipal objective : Validation of a handy biochemical parameter, plasma concentration of Asymmetric DimethylArginine (ADMA), based on a recognize biochemical parameter, the dilation of the brachial artery, at ultrasound examination, after the deflation of a cushion to evaluate …
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New spinal fluid test may sharpen Alzheimer's diagnosis
Diagnosis CompletedThe combined measurement of Ab42 and tau protein (total and phosphorylated) in the spinal fluid has been shown to be promising in the diagnosis of Alzheimer's disease (AD), and has justified its inclusion new diagnostic criteria. However, it can sometimes yield discordant results…
Phase: NA • Sponsor: CHU de Reims • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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Massive european study tracks hemophilia in kids to unlock better care
Knowledge-focused Recruiting nowRationale: Haemophilia is a rare disease; to improve knowledge international collaboration is needed. Well-defined clinical data will be collected from complete cohorts in order to prevent selection bias. Objective: To collect data on bleeding during neonatal period, endogenou…
Sponsor: PedNet Haemophilia Research Foundation • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:47 UTC
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New throat device aims to help people with severe swallowing issues eat without choking
Disease control TerminatedBiomedical devices, such as artificial joints and pacemakers, are accepted and commonly used in medicine. While great progress in biomedical devices has been made for many other disorders, there is currently no device available to assist with the act of deglutition. The investiga…
Phase: NA • Sponsor: Peter Belafsky, MD • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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New EDS registry aims to unlock secrets of rare connective tissue disorder
Knowledge-focused Recruiting nowRED is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains: personal information, clinical data, genetic data, gene…
Sponsor: Luca Sangiorgi • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Blood test may predict heart attack Patients' future risk
Knowledge-focused CompletedThis prospective study aimed to validate a new prognostic approach of endothelial progenitor cells associated biomarkers in patients with acute coronary syndromes . Recruitment is made prospectively by two centers of Inter -region South Mediterranean,
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New muscle measurement method tested in seniors
Knowledge-focused TerminatedCurrent methods for the quantification of muscle mass are indirect, lack precision, and often rely on expensive equipment that only provides limited (indirect) data on whole body muscle mass. Dual energy X ray absorptiometry has emerged as a potential precise measure of lean mass…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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15,000 cancer Patients' data to unlock surgery secrets
Knowledge-focused Recruiting nowThis retrospective study aims at evaluating the outcomes of gastrointestinal stromal tumor after surgery.
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Thousands join fight against blindness by sharing their stories
Knowledge-focused Recruiting nowThe My Retina Tracker® Registry is sponsored by the Foundation Fighting Blindness and is for people affected by one of the rare inherited retinal degenerative diseases studied by the Foundation. It is a patient-initiated registry accessible via a secure on-line portal at www.MyRe…
Sponsor: Foundation Fighting Blindness • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Baby formula upgrade: could lactoferrin close the gap with breast milk?
Knowledge-focused CompletedBreast milk is the gold standard of early infant nutrition and breastfed infants have advantages in several short and long term outcomes compared to those formula-fed. The first aim of this study is to evaluate the effect of adding bovine lactoferrin to infant formula. The gener…
Phase: NA • Sponsor: Umeå University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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ICU patients may need custom doses of common antifungal
Knowledge-focused CompletedInvasive fungal infections (IFIs) are a frequent cause of morbidity and mortality in high-risk patients, such as immunocompromised patients. Candida is currently the predominant fungal pathogen in these patient populations and is associated with significant morbidity and a high m…
Phase: PHASE4 • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Massive lung disease registry aims to unlock secrets of progressive fibrosis
Knowledge-focused Recruiting nowThe Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) Registry started recruiting in 2014 with the objective of studying Idiopathic Pulmonary Fibrosis. In 2018, the registry expanded to include recruitment of participants with other chronic fibrosing interstitial lung …
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Spine surgery breakthrough: new nerve monitoring method tested
Knowledge-focused CompletedThough the utility of NVM5 neuromonitoring by stimulating within the surgical site during XLIF has been demonstrated, it is hypothesized that more information may be gathered if a greater section of the motor neural pathway was monitored (i.e., stimulation above the surgical site…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC