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116076 trials found · Page 5146 of 5804
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Steroid or painkiller shot: which works better for thumb tendonitis?
Symptom relief CompletedThe purpose of this study is to determine if corticosteroid injection modifies the natural course of de Quervain tendinopathy compared to a toradol injection.
Phase: PHASE4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Prolapse surgery goes Same-Day: small study tests feasibility
Knowledge-focused CompletedDay surgery is performed in the same way as in full hospital admission, allowing same-day discharge without increased risk. It provides many grounds for patient satisfaction. Progress in surgical and anesthesia techniques now allows this form of management to be developed and pri…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:14 UTC
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Can proton radiation save Kids' brainpower? new study aims to find out
Knowledge-focused Recruiting nowThis study will explore neurocognitive performance in pediatric brain tumor patients receiving proton beam radiation therapy (PBRT). The investigators goal is to gather baseline neurocognitive testing prior to the completion of the first week of radiation therapy along with follo…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Scientists investigate immune cell defects in rare blood vessel disease
Knowledge-focused CompletedGiant cell arteritis (GCA) is the most frequent vascularitis after 50 years of age The investigators recently showed that GCA was accompanied by an elevation in Th1 and Th17 response \[1\]. Even though a quantitative deficit in regulatory TL (Treg) was shown, there are to date no…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Immune cell study could pave way for new arthritis treatments
Knowledge-focused CompletedRecently, it has been shown that B cells could also have regulatory functions through the secretion of interleukin 10 (IL-10). They are called the B regulatory cells (Breg). In the mouse model the most commonly used of rheumatoid arthritis, collagen-induced arthritis (CIA), the t…
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Brain scan study aims to sharpen diagnosis of neurological diseases
Knowledge-focused CompletedWhite matter tracts connect cortical areas to other parts of the cortex, to basal ganglia and to the brain stem and spinal cord. These tracts form the internal part of the brain and transmit the nervous impulses. Changes in brain white matter may serve as biomarkers for numerous …
Phase: NA • Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Space gut check: probiotics studied on ISS crew
Knowledge-focused CompletedHuman immune function and intestinal microbiota are suggested to be altered within long-duration stay in space. Accumulated evidences on earth support that Lacticaseibacillus paracasei strain Shirota (LcS) is a promising probiotic strain on improvement of immune function and inte…
Phase: NA • Sponsor: Yakult Honsha Co., LTD • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Dashboard tool aims to streamline sarcoma care
Knowledge-focused CompletedThis clinical trial investigates whether measuring and presenting information about a patient's cancer treatment to them, their doctor, and their radiologist using a tool called an "oncology dashboard" may help patients understand the disease better and help the patient's medical…
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New pain combo could cut morphine use after Open-Heart surgery
Symptom relief CompletedSternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine. The analgesic efficacy of continuous wound infiltration at the sternum following heart surgery has …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Shingles nerve pain linked to higher dementia risk in massive study
Knowledge-focused CompletedThis retrospective observational cohort study uses de-identified electronic health record data from the TriNetX Global Collaborative Network to evaluate whether postherpetic neuralgia after herpes zoster is associated with an increased risk of incident dementia. Adults aged 40 to…
Sponsor: China Medical University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Breast cancer chemo study tracks calcium and vitamin changes
Knowledge-focused CompletedThis study is to Assess hypercalciuria between J1 of the cure and 1 J1 6 of the cure of adjuvant chemotherapy in patients receiving conventional adjuvant chemotherapy of breast cancer.
Phase: NA • Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Ear fluid study aims to identify Infection-Causing bacteria in kids
Knowledge-focused Recruiting nowAfter pneumococcal conjugate vaccine implementation, the number of acute otitis media (AOM) episodes has decreased, but AOM still remains among the most common diagnoses in childhood. From 2% to 17% of cases of AOM feature spontaneous perforation of the tympanic membrane (SPTM). …
Sponsor: Association Clinique Thérapeutique Infantile du val de Marne • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Pen and paper may boost immunity in seniors
Knowledge-focused CompletedUCLA researchers looking for healthy females (age 60+) to participate in a study investigating how writing about your experiences may be related to your health. Once a week for 6 weeks, participants will write about their experiences and fill out online questionnaires. Participa…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New biopsy method may predict cancer spread without surgery
Knowledge-focused CompletedAll the preoperative biopsies of patients suffering colorectal cancer (CRC) will be immunohistochemically stained with a pancytokeratin marker to detect Tumor buds. then, the intratumoral buds (ITB) in the densest Region of Tumor buds, namely the "hot spot" will be counted. Subse…
Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New blood tests could improve gaucher disease monitoring
Knowledge-focused Recruiting nowThe objective of this study is to evaluate oxidative stress and/or inflammation in patients with Gaucher disease type I using a series of biomarkers and correlate with measurements of currently used diagnostic biomarkers.
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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New algorithm aims to speed up diagnosis of mysterious high white blood cell counts
Knowledge-focused CompletedEosinophilia, defined by a blood eosinophil granulocytes rate greater than 500 / mm3, is frequently encountered in internal medicine. Its causes are varied: atopy, drug allergies, parasitic infections, autoimmune diseases and solid neoplasias. Over 200 etiologies have been repor…
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Massive U.S. registry aims to unlock secrets of pulmonary hypertension care
Knowledge-focused Recruiting nowThe PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary …
Sponsor: Pulmonary Hypertension Association, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Exercise in pregnancy shows promise for overweight moms
Disease control CompletedThe main objective of this project is to assess the effects of a novel and supervised exercise intervention in overweight pregnant and their newborn. Methods/Design: The present study is a Randomized Controlled Trial. Sixty overweight pregnant interested in participate in the in…
Phase: NA • Sponsor: Universidad de Granada • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Hard-to-Place breathing tubes may raise pneumonia risk
Knowledge-focused CompletedThe investigator wants to investigate if there is an increased risk of postoperative pulmonary problems in patients who have had an intubation where there was need for more than a laryngoscope.
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Massive study tracks heart damage after surgery in nearly 20,000 patients
Knowledge-focused OngoingThis observational study includes patients undergoing major non-cardiac surgery, and screens them for the occurrence of perioperative myocardial injuries (PMI). Incidence, patient characteristics, pathophysiology, potential prevention and therapy strategies and 1-year outcomes of…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC