New cancer drug PM54 enters first human tests
NCT ID NCT05841563
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase trial is testing an experimental drug called PM54 in people with advanced solid tumors that have not responded to standard treatments. The study has two parts: first, finding a safe dose by watching for side effects, and second, checking if the drug can shrink tumors. About 125 adults will take part, and the drug is given through an IV.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PM54 (an experimental drug given by IV infusion)
- What this could lead to
- If it works, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.
- What could go wrong
- This is a very early Phase 1 trial with only 125 participants, so the main goal is safety, not effectiveness. Many experimental drugs fail at this stage, and side effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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HM Universitario Sanchinarro
RECRUITINGMadrid, M, 28050, Spain
Contact
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Institut Jules Bordet
RECRUITINGAnderlecht, 1070, Belgium
Contact
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South Texas Accelerated Research Therapeutics
RECRUITINGSan Antonio, Texas, 78229-3307, United States
Contact
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