Timing matters: menstrual cycle may influence breast cancer treatment choices

NCT ID NCT05878314

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the menstrual cycle and preoperative hormone therapy affect a marker called Ki67 in women with early hormone-positive breast cancer. Researchers will also see if adding a genetic test (PAM50) changes treatment recommendations. About 504 women will participate, and the goal is to better personalize adjuvant therapy decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors personalize adjuvant treatment decisions for hormone-positive breast cancer patients.

What could go wrong

This is an observational study, not a treatment trial. It may not directly change patient outcomes or lead to new therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Women's Health

    RECRUITING

    Tübingen, 72076, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••