Timing matters: menstrual cycle may influence breast cancer treatment choices

NCT ID NCT05878314

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the menstrual cycle and preoperative hormone therapy affect a marker called Ki67 in women with early hormone-positive breast cancer. Researchers will also see if adding a genetic test (PAM50) changes treatment recommendations. About 504 women will participate, and the goal is to better personalize adjuvant therapy decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors personalize adjuvant treatment decisions for hormone-positive breast cancer patients.
What could go wrong
This is an observational study, not a treatment trial. It may not directly change patient outcomes or lead to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Women's Health

    RECRUITING

    Tübingen, 72076, Germany

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