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127005 trials found · Page 5130 of 6351
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Which technique best finds hidden breast lesions? study aims to find out
Knowledge-focused OngoingBreast conservative surgery (BCS) is nowadays the standard of care for patients affected by early breast lesions. Screening programmes led to an increase of non-palpable breast lesion detection rates. These patients are often eligible for BCS and an accurate preoperative localiza…
Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Can stress during pregnancy raise diabetes risk?
Knowledge-focused OngoingDuring pregnancy, gestational diabetes increases the risk of complications and adverse outcomes for mother and child, however about 50% of gestational diabetes cases are diagnosed without a known risk factor present. This project uses both a large sample retrospective study, and …
Sponsor: Sanford Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Scientists hunt for leaky vessel clues in ICU patients
Knowledge-focused Recruiting nowBACKGROUND Controlling vascular leakage, which is independently associated with mortality during Sepsis and cardiogenic shock, may be a promising approach during systemic inflammatory response syndrome (SIRS). During a collaborative work between La Pitié-Salpêtrière intensive car…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Scientists uncover DNA's hidden role in Kids' gut disease
Knowledge-focused CompletedFrequency of Inflammatory Bowel Diseases in children (IBD)-Crohn's disease (CD), Ulcerative colitis (UC) is constantly increasing. Pediatric-onset IBD represent a different nosological entity (from adult IBD) because of their major inflammatory activity, their significant anatomi…
Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Are elderly ER patients missing out on palliative care?
Knowledge-focused OngoingAim: To assess what proportion of all patients over the age of 75 who seek care at the emergency department have palliative care needs and whether these are documented in the patient's medical record. Data collection and analysis: Patients over 75 years of age who seek care in a…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Aortic Stent-Graft safety under the microscope: 600-Patient european registry launches
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate the safety and performance of Cook's various Custom-Made Stent-graft Devices (CMD) used for endovascular treatment of the aorta and related diseases by collecting information on the real-world use of the devices. The study results will be…
Sponsor: Cook Research Incorporated • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Can educating parents shield kids from skin cancer?
Knowledge-focused CompletedIntroduction: Cancer is a serious disease with a high mortality rate in the world and in Turkey today. Skin cancer, which is among the most common types of cancer, is increasing every year in many countries in the world such as Australia, America, New Zealand, and in Turkey. The …
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Simple 5-Minute exam may spot hidden pelvic damage after cancer radiation
Knowledge-focused Stopped earlyThe two goals of this study are to establish a standardized method of assessing the pelvic floor for patients undergoing pelvic radiation and to determine the feasibility of inverse-RT planning using MRI to identify dosimetric constraints of the pelvic floor musculature for use i…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Sound waves vs. stroke spasticity: scientists probe how it works
Knowledge-focused CompletedSpasticity, common after a stroke, aggravates the patient's motor impairment causing pain and limitation in daily activities such as eating, dressing and walking. There are different spasticity treatments, such as botulinum neurotoxin, in the first place. Among the emerging ther…
Sponsor: Istituto Auxologico Italiano • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Simple blood test may uncover rare diseases in myeloma patients
Knowledge-focused Recruiting nowThe study of splenomegaly, and the follow-up of splenectomized patients, is one of the causes of referral of these patients to pediatric gastroenterology and oncohematology clinics, and adult internal medicine and hematology. The study and management of splenomegaly is well descr…
Sponsor: Fundación Española de Hematología y Hemoterapía • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Blood test may forecast life-threatening clots or bleeds on ECMO
Knowledge-focused CompletedTo study the correlation between novel DIC markers and thrombin generation parameters with thrombotic and hemorrhagic complications of patients on ECMO support.
Sponsor: Queen Mary Hospital, Hong Kong • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Can tech and coaching get more diabetes patients into education?
Knowledge-focused CompletedThis is a pilot and feasibility study of a pragmatic cluster randomized trial that utilizes health information technology and practice facilitation to address referral barriers and increase clinician awareness and motivation to refer patients with diabetes to diabetes self-manage…
Sponsor: Mary Lacy • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Tapping away fear: simple technique may ease Post-Meal anxiety in eating disorders
Symptom relief CompletedThe goal of this clinical trial was to evaluate whether bilateral stimulation (BLS) could reduce anxiety and emotional distress after eating in people recovering from eating disorders in outpatient treatment with the primary researcher. The main question it aimed to answer were:…
Sponsor: San Francisco State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Amino acids may change how the body controls blood sugar
Knowledge-focused OngoingThis study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.
Phase 4 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Knee patients try personalized goal program to boost treatment success
Symptom relief OngoingTo evaluate the effectiveness of the goal development intervention in guiding individual patients through the identification of high quality, specific, measurable, relevant and time-bound goal for treatment.
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Sep 02, 2026 00:00 UTC
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Gum surgery upgrade: enamel proteins and bone graft show promise
Disease control CompletedThe present three-arm study compared the clinical and tomographic efficacy of the Entire Papilla Preservation Surgical Technique (EPPT) alone and combined with enamel matrix derivative (EMD) plus bone mineral derivedxenograph (BMDX), in the treatment of isolated, inter-dental int…
Phase 4 • Sponsor: Rungta College of Dental Sciences and Research • Aim: Disease control
Last updated Jun 26, 2026 17:09 UTC
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Simple stretches may offer Drug-Free relief from menstrual cramps
Symptom relief CompletedThe study aimed to examine the effect of stretching and relaxation exercises on pain and quality of life in women with primary dysmenorrhea.
Sponsor: Yeditepe University • Aim: Symptom relief
Last updated Jun 26, 2026 16:36 UTC
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Talking it out: phone program boosts heart failure Patients' and Caregivers' Well-Being
Symptom relief CompletedThe overall aim of the study is to evaluate the effects of a psychosocial dyadic intervention on mutuality, psychological strengths (i.e., resilience and self-compassion), psychological distress (i.e., anxiety and depression), and QoL outcomes of HF patients and caregivers. The H…
Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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New program aims to help MSA patients and families cope
Symptom relief CompletedMultiple system atrophy (MSA) is a rare neurodegenerative disorder that leads to major disability, forcing patients and caregivers to adapt their environment and lifestyle. Once they receive the diagnosis, patients and caregivers need to understand the symptoms, cope with them, t…
Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Paws for thought: cat training program shows promise for youth with disabilities
Knowledge-focused CompletedThis R21 provides a multidisciplinary One Health approach to developing and evaluating a novel Cat Assisted Training (CAT) animal assisted intervention (AAI) for early adolescents with developmental disabilities (DD) and their family cat. Cat social behavior and welfare is heavil…
Sponsor: Oregon State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC