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127005 trials found · Page 5098 of 6351
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Can a blood test predict who will get diabetes from steroids?
Knowledge-focused OngoingThe excess of glucocorticoid, whether endogenous or exogenous, results in Cushing's syndrome, associating a particular distribution of fats (accumulation in the face and trunk), a decrease in the thickness of the muscles, diabetes, hypertension or osteoporosis. The level of effe…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Fatty liver study tests Insulin-Lowering drug to uncover disease roots
Knowledge-focused CompletedThe goal of this clinical trial is to compare a two-week course of diazoxide (at two different doses) and placebo in people with overweight/obesity and insulin resistance (IR) with, or at high risk for, non-alcoholic fatty liver disease (NAFLD). The main questions it aims to answ…
Phase 1 • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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AI-Powered ultrasound training could save lives in cardiac arrest
Knowledge-focused Recruiting nowThis study aims to establish a novel transesophageal echocardiography (TEE) simulation curriculum based on previous research results and suggestions from the American College of Emergency Physicians. To better evaluate the efficacy of the curriculum, an evaluation model utilizing…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Can a gentle head massage ease your back pain?
Symptom relief CompletedCraniosacral Therapy (CST) is a non-manipulative, very gentle manual treatment method. Although the mechanisms of action have not yet been investigated sufficiently, initial clinical trials support CST efficacy/effectiveness in chronic pain disorders such as back pain, neck pain,…
Sponsor: Universität Duisburg-Essen • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Are pro gamers hurting? new study investigates pain and sleep in E-Athletes
Knowledge-focused CompletedE-Sports, which attract great attention in the media and social networks, brings health problems and some risks, depending on the attractiveness of games and the time spent in the digital world. When the investigators examine the literature, although different studies are showing…
Sponsor: Bandırma Onyedi Eylül University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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500,000 patients join massive gut disease study
Knowledge-focused OngoingTARGET-GASTRO is an observational research study to conduct a comprehensive review of outcomes for patients with the chronic gastrointestinal (GI) diseases: eosinophilic gastrointestinal disease (EGID), ulcerative colitis (UC) or Crohn's disease (CD).
Sponsor: Target PharmaSolutions, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Botswana study reveals hidden link between HIV, EBV, and lymphoma
Knowledge-focused OngoingThis will be a cross sectional, pilot study to determine the burden of EBV related lymphomas in this population. Patient information including demographics and HIV status, history of HIV infection, HIV viral load and CD4 counts and ART history will be retrieved from the integrate…
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Headband that reads your brain waves may ease insomnia in menopausal women
Symptom relief CompletedThe purpose of this study is to see if it is feasible for midlife women to wear a brain activity sensing headband (Muse-S) for management of sleep disturbances such as insomnia and sleep disruption
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Playtime for brainpower: new study tests if active play boosts thinking in Low-Income preschoolers
Knowledge-focused OngoingThe goal of this study will be to examine the implementation and preliminary efficacy of a teacher taught gross motor skill-based physical activity (PA) intervention on cognitive variables in low low socio-economic (SES) preschoolers. The movement and cognition intervention will …
Sponsor: University of Massachusetts, Amherst • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Coloring books in the ER: a simple fix for long waits?
Symptom relief Recruiting nowThe objective of this research is to assess the effects of engaging in coloring activities on patients' self-reported pain and anxiety scores while they wait to be seen by a physician in an emergency department (ED). The current literature on patient visits in the ED highlights t…
Sponsor: Stony Brook University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Can ARVC patients exercise safely? new study aims to find out
Knowledge-focused Recruiting nowCurrent guidelines advocate that ARVC patients, typically young and active individuals with a significant history of competitive endurance sports, cease endurance training in favour of activities with low cardiac burden such as bowling and golf. Empirically, it is often suggested…
Sponsor: Swiss Federal Institute of Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New study tracks 1,500 transplant patients to unlock secrets of a devastating complication
Knowledge-focused Recruiting nowThe purpose of this prospective observational study is to collect data from participants who have recently had an allogenic Stem Cell Transplant(alloSCT) and are at risk of Chronic Graft Versus Host Disease(cGVHD)
Sponsor: Incyte Corporation • Aim: Knowledge-focused
Last updated Aug 27, 2026 00:00 UTC
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Simple night splint may boost trigger finger recovery
Symptom relief Recruiting nowThis study is to analyze the effectiveness of a nighttime extension orthosis after receiving a cortisone injection for the treatment of trigger finger to improve pain and restore functional outcomes. The investigators hypothesize that the extension orthosis will improve pain and …
Sponsor: Cedars-Sinai Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Mindfulness program shows promise for stressed first responders
Knowledge-focused CompletedHigh levels of chronic and recurrent workplace stress can profoundly impact the physical, mental, and emotional health of first responders. A multi-modal evidence-based mindfulness intervention was delivered to cohorts of first responders to evaluate effects on perceived stress, …
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Heart rhythm study probes why some patients tolerate VT better than others
Knowledge-focused Recruiting nowThe goal of this observational study is to learn about the factors which determine how well ventricular tachycardia (VT) is tolerated. The main questions it aims to answer are: 1. What impact does coronary artery disease have on the ability for a patient to tolerate VT? 2. Does …
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New study tracks hidden virus threat in liver transplant patients
Knowledge-focused CompletedThe goal of this observational study is to learn about cytomegalovirus disease epidemiology in pediatric and adult liver transplant recipients in China. The main questions it aims to answer are: * The incidence of Cytomegalovirus (CMV) Infections (including clinical significant …
Sponsor: Lin Zhong • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Group gaming shows promise for dementia symptoms
Symptom relief CompletedThe study examines the effects of a group digital gaming intervention on cognitive function, mood, and behaviors in people with early to moderate levels of dementia, using Obie Technology by employing a pretest and posttest design with a mixed methods approach.
Sponsor: George Mason University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Hip fracture surgery showdown: which plate works best?
Disease control Recruiting nowThe hypothesis of this study is that the Rim Plate method utilizing interfragmentary screws placed through the plate will result in superior fixation, a lower rate of loss of reduction of the fracture fragment, better anatomic healing of the articular (joint) surface, a decreased…
Sponsor: University of Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New combo aims to ease shoulder surgery pain
Symptom relief By invitation onlyThere is a high incidence reaching up to 45%; of severe intraoperative and postoperative pain associated with arthroscopic shoulder surgery, which is often significant enough to interfere with initial recovery and rehabilitation.Various peripheral nerve blocks have been used to r…
Phase 2/3 • Sponsor: New Valley University • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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New heart artery map could speed up Life-Saving tests
Knowledge-focused Recruiting nowIn patients with 50-90% stenosis of the coronary artery, the coronary roadmap (dynamic roadmap) is performed when the conventional fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are performed. coronary roadmap system) to confirm the effectiveness of the fun…
Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC