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116076 trials found · Page 5048 of 5804
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Nerve activity study aims to unlock stomach disorder secrets
Knowledge-focused TerminatedGastroparesis Patients and Healthy Controls ages 20-49 will be asked to participate in an observational study measuring vagal activity following food ingestion in order to establish parameters of autonomic nerve/vagal function in healthy human subjects compared to those with gast…
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:22 UTC
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Hidden diabetes complication under the microscope: charcot foot care revealed
Knowledge-focused CompletedDespite the prominence of diabetes prevalence (more than 8% of the world population in 2012) and its expected increase in the next 15 years, Charcot foot remains a widely unknown diabetes complication. At this day, there is no national guidelines about diagnosis and treatment of …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Brain zaps for better sleep? small trial tests DBS for Parkinson's insomnia
Symptom relief Recruiting nowResearchers are to determine if turning on an additional unilateral DBS (deep brain stimulation) electrode with stimulation to the globus pallidus externa (GPe) region of the brain will improve insomnia (sleep).
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Massive new registry aims to improve survival of tiniest babies
Knowledge-focused Recruiting nowThe goal of the Tiny Baby Collaborative Multicenter Inventory of Neonatal-Perinatal Interventions (MINI) minimum dataset is to serve as a registry detailing the outcomes and practices for all deliveries and infants admitted to intensive care at 22-23 weeks' gestation at participa…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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500 patients join hunt for genetic clues in brain vessel disease
Knowledge-focused Recruiting nowThe TAG-SVD enrolled patients with clinical and neuroimaging features of cerebral small vessel disease (CSVD). All enrolled patients will receive next-generation sequence (NGS) with probes designed to target five candidate CSVD genes, and patients will be divided into genetic or …
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Premature baby lung study aims to predict breathing risks
Knowledge-focused OngoingThe purpose of this study is to examine if infants are more likely to suffer from respiratory complications during their first year of life due to being born premature.
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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MRI scans reveal hidden clues in complex knee fractures
Knowledge-focused CompletedThis retrospective observational case-control study aims to evaluate imaging features and associated soft-tissue injury patterns in patients with Schatzker type IV tibial plateau fractures. Adult patients treated surgically at a single tertiary trauma center between January 2019 …
Sponsor: Second Affiliated Hospital of Soochow University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Kawasaki Kids' hearts under the microscope 5 years later
Knowledge-focused CompletedThe aim of present study is to determine cardiovascular status of children who had KD in past and to identify possible biochemical markers of cardiovascular damage in those patients. In this cross-sectional study children with history of KD will be examined 5 years after receivi…
Sponsor: Medical University of Warsaw • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Why does colon cancer hit young people differently?
Knowledge-focused Recruiting nowA Study on the Characteristics of Colorectal Cancer by Age and sex.
Sponsor: Seoul National University Bundang Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New registry aims to improve care for fractures near joint implants
Knowledge-focused Recruiting nowThis registry supports international data collection and research on PPFx treatments after hip and knee arthroplasty. A registry such as this ultimately aims to provide far-reaching benefits to society including reduced morbidity and mortality, improved patient safety, improved …
Sponsor: AO Innovation Translation Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:53 UTC
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Your morning coffee might affect your eye health – new study investigates
Knowledge-focused Recruiting nowCaffeine is the most widely consumed drinking nutrient in the world. Caffeine effects various organs and the vascular system. It decreases ocular blood flow due to vasoconstriction.
Phase: NA • Sponsor: Wills Eye • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Leg ulcer oxygen mystery: Compression's hidden effect revealed
Knowledge-focused CompletedArterio-venous leg ulcers are real problems when it comes to public health because it has a major cost and leads to social and professional handicap. The management of leg ulcers is not clear and can be venous compression or surgery. The aim of the study is to evaluate the vari…
Phase: NA • Sponsor: University Hospital, Caen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New registry monitors heart transplant patients for better rejection detection
Knowledge-focused OngoingThis is an observational registry to assess the clinical utility of surveillance using HeartCare testing services, in association with clinical care of heart transplant recipients.
Sponsor: CareDx • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Can a custom diet for kids prevent future disease?
Knowledge-focused OngoingInvestigating glucose response to Mediterranean and regular diets in healthy children in order to develop specific pediatric machine-learning for predicting the personalized glucose response to food for individual children. The prediction will be based on multiple measurements, …
Sponsor: Weizmann Institute of Science • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Which tool is best for removing clot traps? a new study aims to find out
Knowledge-focused Recruiting nowIVC filters are mechanical filters placed in a patient's body to trap blood clots in the legs migrating to the lungs. When no longer indicated, interventional radiologists are consulted for IVC filter removal. Currently, many methods for extracting IVC filters exist. Two of the m…
Phase: NA • Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Molar pregnancy mystery: to treat or not to treat lung nodules?
Knowledge-focused Recruiting nowThe purpose of present study is to provide clinical evidences for the appropriate management of molar pregnancy with lung nodule. The hydatidiform mole patients with lung nodule ≥1.0cm will be randomized into 2 groups: A. treated with chemotherapy immediately, B. follow up until …
Phase: NA • Sponsor: Women's Hospital School Of Medicine Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Can poop predict preemie health? new study investigates
Knowledge-focused OngoingPremature infants are at risk for a variety of diseases, the investigators would like to learn more about why some premature babies are at higher risk and some are protected from these diseases. Scientists at UC Davis and other universities have developed new ways to measure the…
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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15,000 skin patients enrolled in massive Real-World treatment study
Knowledge-focused OngoingTARGET-DERM is a longitudinal, observational study of adult and pediatric patients being managed for Atopic Dermatitis and other Immune-Mediated Inflammatory Skin Conditions (IMISC) in usual clinical practice. TARGET-DERM will create a research registry of patients with IMISC wit…
Sponsor: Target PharmaSolutions, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Scientists track drug behavior in severe colitis patients
Knowledge-focused OngoingThis is an open-label, prospective, observational study with the primary objective to characterize the pharmacokinetics of infliximab in patients with Acute Severe Ulcerative Colitis.
Sponsor: Alimentiv Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Inhaled treprostinil safety trial for PH-COPD ends early
Disease control TerminatedThis open-label study will evaluate the safety of continued therapy with inhaled treprostinil in participants who have completed Study RIN-PH-304 (NCT03496623). This study hypothesizes that long-term safety findings will be similar to those observed in the randomized, placebo-con…
Phase: PHASE3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC