Could your body shape change how chemo works?
NCT ID NCT05858398
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether body composition (fat and muscle) changes how the chemotherapy drug docetaxel behaves in women with early breast cancer. Researchers will compare drug levels in obese, overweight, and lean patients using blood samples and CT scans. The goal is to see if current dosing based on body surface area needs adjustment for body fat.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
docetaxel
What this could lead to
If successful, this could help doctors personalize docetaxel dosing based on body composition, potentially reducing side effects and improving treatment effectiveness.
What could go wrong
This is a small, early-phase observational study (48 participants) that only measures drug levels, not treatment outcomes. Results may not change clinical practice without larger trials.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre Henri Becquerel
RECRUITINGRouen, 76038, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••