Could your body shape change how chemo works?
NCT ID NCT05858398
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether body composition (fat and muscle) changes how the chemotherapy drug docetaxel behaves in women with early breast cancer. Researchers will compare drug levels in obese, overweight, and lean patients using blood samples and CT scans. The goal is to see if current dosing based on body surface area needs adjustment for body fat.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- docetaxel
- What this could lead to
- If successful, this could help doctors personalize docetaxel dosing based on body composition, potentially reducing side effects and improving treatment effectiveness.
- What could go wrong
- This is a small, early-phase observational study (48 participants) that only measures drug levels, not treatment outcomes. Results may not change clinical practice without larger trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre Henri Becquerel
RECRUITINGRouen, 76038, France
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