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116076 trials found · Page 4950 of 5804
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Which insulin dosing method works best for cystic fibrosis diabetes?
Disease control CompletedThe aim of this study is to assess the utility of CGMs to determine the optimal method to dose meal-time insulin. The investigators will examine glucose excursions in patients with CF who will dose meal-time rapid-acting insulin by carbohydrate counting versus fixed-dose rapid-ac…
Phase: PHASE4 • Sponsor: Jagdeesh Ullal • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Exercise boosts energy in cancer patients, study finds
Symptom relief CompletedThe objective of this study is to evaluate the effects of regular physical practice on fatigue, quality of life and kinesiophobia in patients treated at the ICO in Angers, regardless of the type of cancer and the type of treatment.
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Glowing dye could predict bone infections after fractures
Knowledge-focused CompletedThe focus of this prospective observational study is to (1) establish the range and variation associated with bone/soft tissue perfusion in fracture patients, using ICG fluorescence imaging; (2) examine the relationship between perfusion and complications such as surgical site in…
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Pregnancy diet study aims to fill amino acid gap
Knowledge-focused CompletedThe current recommendations for dietary amino acid intake in pregnant women are based on calculations from requirements of adult men. The study aims to determine methionine requirements during early (11-20 weeks) and late (31-38 weeks) stages of pregnancy. Methionine, an essentia…
Phase: NA • Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Kimchi and yogurt: a new hope for gut inflammation?
Symptom relief Recruiting nowThe purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal …
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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New catheter system tested for safer heart defect repair
Disease control CompletedA single-arm, non-randomized, multi-center clinical study of the Amplatzer™ Trevisio™ Intravascular Delivery System for facilitating percutaneous, transcatheter implantation of the Amplatzer™ Occluder Devices.
Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Lung cancer Treatment's hidden heart risk under the microscope
Knowledge-focused OngoingThis observational cohort will evaluate the cardiovascular effects of chemoradiation used to treat locally advanced, non-small cell lung cancer. Patients will be enrolled prior to the start of therapy and followed during and for at least 2 years after therapy with echocardiograms…
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Teen sun safety study shows promise in reducing skin cancer risk
Prevention CompletedThe purpose of this study is to determine the efficacy of the Sun-safe Habits Intervention and Education (SHINE) intervention in improving sun protection use and decreasing intentional tanning among high school students. It's anticipated that 30 schools will be randomized into th…
Phase: PHASE3 • Sponsor: University of Utah • Aim: Prevention
Last updated Jun 27, 2026 07:54 UTC
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Real-World study checks how well tofacitinib controls ulcerative colitis
Disease control CompletedThis is a prospective observational study using data from an existing, ongoing National Swedish registry (SWIBREG). This study is designed to assess the effectiveness and treatment adherence of tofacitinib on clinical disease activity parameters in patients with ulcerative coliti…
Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Online training aims to ease paramedic burnout and PTSD
Symptom relief CompletedThe purpose of this study is to compare the effectiveness of two different online education courses (Oxford-Online and Mind-Online) for preventing stress related conditions among paramedics who have been working during a period of COVID-19 occurrence in Singapore. The study aims…
Phase: NA • Sponsor: Singapore General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Cancer's hidden cost: study probes financial toxicity
Knowledge-focused OngoingThis study will seek to generate the early data needed to understand the relationship between constructs and measures of patients' coping resources and psychological response and measures of patients' financial toxicity. To collect this early descriptive data, the overall goal of…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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No tourniquet, less pain: new combo approach for hand surgery
Symptom relief CompletedThe carpal tunnel release (CTR) is now performed almost exclusively under regional anesthesia (RA) in France. RA requires the use of a pneumatic tourniquet to limit blood flow to the operated extremity and create a bloodless surgical field for a clear visualization of the anatomi…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Mammograms may soon double as heart disease screenings
Knowledge-focused TerminatedThe goal of this observational study is to assess if there is an association between the presence of BAC and traditional cardiovascular risk factors and validate a Convolutional Neural Network (CNN) for the automatic segmentation of Breast Arterial Calcifications (BAC) in mammogr…
Sponsor: IRCCS Policlinico S. Donato • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:05 UTC
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Could a blood pressure boost save brain cells during a stroke?
Disease control TerminatedAn open label, prospective, single center, pilot trial to assess feasibility and tolerability of short term blood pressure augmentation to minimize infarct progression in acute LVO stroke patients undergoing endovascular therapy.
Phase: EARLY_PHASE1 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 26, 2026 14:05 UTC
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Nurse Follow-Up may boost quit rates in COPD smokers
Disease control Ongoinga monocentric study to evaluate the efficacy of a longitudinal nursing follow up in smoking cessation in patients screened for Chronic obstructive pulmonary disease (COPD).
Sponsor: Centre Hospitalier de Valence • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Texas biorepository aims to unlock Cancer's secrets
Knowledge-focused Recruiting nowThe purpose of the Texas Immuno-Oncology Biorepository (TIOB) is to collect and store well-defined and well-annotated serial biospecimens of tissue, blood, urine and stool in a longitudinal manner from cancer patients who are receiving either standard of care surgical interventio…
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New breath test could replace painful lung scopes
Knowledge-focused ENROLLING_BY_INVITATIONAirway pH imbalances cause numerous adverse physiological changes within the airways, including hyperreactivity, cough, bronchoconstriction, ciliopathy, decreased response to bronchodilators, bacterial growth, nitrosative/oxidative stress, neutrophilic/eosinophilic inflammation, …
Phase: PHASE2 • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Study reveals which leg muscles matter most for balance in older women
Knowledge-focused CompletedPostural stability is a key determinant of functional independence in elderly populations, particularly among women due to age-related declines in muscle strength and balance. Despite recognition of the lower limb musculature's importance in balance, the specific contributions of…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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New study aims to uncover why sleep apnea harms the heart and brain
Knowledge-focused CompletedObstructive sleep apnea (OSA) is a highly prevalent disorder with adverse neurocognitive and cardio-metabolic outcomes. Continuous positive airway pressure (CPAP) is the gold standard therapeutic option to treat airway obstructions during sleep and thus, prevent its adverse cardi…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New study aims to wash away Trauma-Related feelings of dirtiness
Symptom relief Recruiting nowMental contamination-an internal experience of dirtiness evoked in the absence of physical contact with an external source-has been linked to the development and maintenance of posttraumatic stress disorder (PTSD) following exposure to sexual abuse or assault (Adams et al., 2014;…
Phase: NA • Sponsor: Christal L Badour • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC