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116076 trials found · Page 4945 of 5804
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Could three doses a day prevent clots in pregnancy better than two?
Disease control Recruiting nowPregnancy is associated with a increased risk of developing blood clots. There is nearly a 5 times greater risk of developing a blood clot in pregnancy. Lovenox is a medication that helps to prevent the body from developing clots. It is safe to use in pregnancy. Previous studies …
Phase: PHASE4 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Laser therapy could get aching pilots back in the sky faster
Symptom relief TerminatedDetermine the most effective and efficient treatment protocols for treating neck pain with LLLT.
Phase: NA • Sponsor: Paul Crawford • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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How ready are medics for a chemical attack? new study aims to find out
Knowledge-focused ENROLLING_BY_INVITATIONObservation study measuring medical response in contaminated environment.
Sponsor: St. Justine's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Spine implant safety under the microscope: 1,050 patients enrolled
Disease control ENROLLING_BY_INVITATIONThe objective of this study is to evaluate the safety and performance of NuVasive interbody implants when used during thoracic and/or lumbar spine surgery as measured by reported complications, radiographic outcomes, and patient-reported outcomes. This study is being undertaken t…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New approach to muscle relaxants could make breathing machines safer
Knowledge-focused Recruiting nowPNEUMA is a preliminary safety and feasibility trial of a novel approach to the titration of neuromuscular blockade (NMB) to safe spontaneous breathing in patients with moderate to severe acute hypoxemic respiratory failure (AHRF) supported with invasive mechanical ventilation.
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Scientists peek inside the brain to see how speech works in Parkinson's and tremor patients
Knowledge-focused Recruiting nowIn this research study the researchers want to learn more about brain activity related to speech perception and production.
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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10,000 lupus patients needed for landmark online study
Knowledge-focused Recruiting nowSummary The Lupus Foundation of America (LFA) Research Accelerated by You (RAY) Registry is a fully remote, longitudinal registry designed to collect data from adults and children living with lupus. The primary goal is to better understand the diagnosis, treatment, care, and qual…
Sponsor: Lupus Foundation of America • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Shorter catheter use after colorectal surgery may cut infection risk
Knowledge-focused Recruiting nowThis study is being conducted to determine the length of time a urinary catheter is needed to drain urine from the bladder after colorectal surgery. Urinary retention is a well known complication after pelvic colorectal surgery, and current practice is to continue urinary cathete…
Phase: NA • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Even on blood thinners, strokes happen – study investigates why
Knowledge-focused CompletedThis study is aimed to depict the epidemiological trend, aetiologies, clinical characteristics, treatment options of IS-NOAC in face of the rapidly increasing NOAC usage. Knowledge on this ischaemic stroke entity will define clinical characteristics, identify preventable causes a…
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Rehab showdown: which therapy eases back pain from slipped vertebrae?
Symptom relief CompletedThis interventional clinical study evaluated the effectiveness of two different 4-week rehabilitation programs in older adults aged 60-75 years with radiologically confirmed grade I or II spondylolisthesis. Participants were assigned to one of two parallel treatment groups. One g…
Phase: NA • Sponsor: Józef Piłsudski University of Physical Education • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Hip scope vs. new hip: which surgery wins for early arthritis?
Disease control TerminatedThe aim of the proposed study is to perform a comparative pilot, randomized controlled trial of hip arthroscopy versus definitive total hip arthroplasty (THA) for the treatment of early hip osteoarthritis (Tönnis Grade 1-2) in patients between the ages of 40-60 years.
Phase: NA • Sponsor: Western University, Canada • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Gum inflammation linked to eye disease in small study
Knowledge-focused CompletedThis cross-sectional observational study aimed to evaluate periodontal clinical parameters and inflammatory cytokine levels in gingival crevicular fluid (GCF), saliva, and serum in patients with non-infectious uveitis (NIU) compared with systemically healthy individuals. Twenty-…
Sponsor: Selcuk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Heart attack patients monitored for hidden rhythm disorder
Knowledge-focused Recruiting nowTo validate the prognostic importance of the burden of new-onset atrial fibrillation (NOAF) complicating acute myocardial infarction (AMI) in a prospectively designed hospital-based registry. To characterize those factors that contribute to the progression of post-MI NOAF burden.…
Sponsor: Shanghai 10th People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Elastic tape might ease pain of broken collarbones in children
Symptom relief OngoingClavicle fractures in children are mostly managed non-operatively since they have an overall high union rate (95%) and a "good" functional outcome following nonoperative treatment. However, the downside of such a conservative approach is that patients have to live with pain and d…
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Massive study tracks hidden dangers for kids with heart defects undergoing other surgeries
Knowledge-focused Recruiting nowThe incidence of moderate to severe congenital heart disease (CHD) in the United States is estimated to be 6 per 1000 live-born full term infants. Recent advances in pediatric cardiology, surgery and critical care have significantly improved the survival rates of patients with CH…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Which works best for trigger finger: injection or minor surgery?
Symptom relief OngoingThis is a prospective randomized multicenterstudy focusing on PROMs after primary corticoid injection for triggerfinger with a comparison of two different injection techniques.
Phase: NA • Sponsor: Sahlgrenska University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Tonsil infection showdown: surgery vs. drainage
Disease control TerminatedThe diagnosis and treatment of tonsillar abscess are very physician-dependent, as sufficient prospective medical literature is lacking to choose the most efficient regimen. The proposed study aims to assess the therapeutic efficacy of tonsillectomy compared to drainage under loca…
Phase: NA • Sponsor: University Hospital, Geneva • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New online training could speed up swallowing checks for stroke patients
Knowledge-focused CompletedStroke is a leading cause of death and disability globally. Dysphagia, swallowing difficulty, is common following stroke, affecting about 55% of all stroke patients. People with stroke and dysphagia are three times more likely to develop pneumonia compared to patients with no dys…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Blood marker may predict IBD Flare-Ups
Knowledge-focused Recruiting nowWe attempt to examine the association between serum leucine-rich alpha-2 glycoprotein (LRG) levels and endoscopic activity in patients with possible ulcerative colitis (UC) or Crohn's disease (CD) to determine whether LRG was a predicting marker for UC or CD.
Sponsor: Showa Inan General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Heart scan tracer may reveal Chemo's effect on amyloid buildup
Disease control TerminatedThis is a pilot study designed to assess for relative change in cardiac 18F Florbetapir uptake in patients with AL cardiac amyloidosis after appropriate chemotherapy.
Phase: PHASE4 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC