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127005 trials found · Page 4900 of 6351
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Could a simple survey improve diabetes care for teens?
Symptom relief OngoingThe goal of this clinical trial is to compare the Spotlight AQ survey platform to the standard of care (SOC) pre-clinic assessment in adolescents \& young adults (16-25 years old) with Type 1 Diabetes (T1D). The main questions it aims to answer are: * Does using the Spotlight A…
Sponsor: Children's Mercy Hospital Kansas City • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Can softer bristles better clean around dental implants?
Disease control CompletedPeri-implant mucositis is a reversible inflammatory condition primarily caused by biofilm accumulation around dental implants. Effective plaque control is essential for disease resolution; however, the influence of toothbrush bristle design on plaque removal around implant-suppor…
Sponsor: Octavi Camps-Font • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Hockey players test Brain-Body drills to skate safer and stronger
Knowledge-focused Recruiting nowThe goal of this study is to evaluate the effects of SM/NM training in ice hockey players. The specific questions include: 1) typical performance on sensorimotor and neuromuscular (SM/NM) tests 2) evaluate SM/NM training on ice hockey skills performance and SM/NM tests, 3) evalua…
Sponsor: Sport Injury Prevention Research Centre • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Hearing test may spot early signs of memory decline
Knowledge-focused Recruiting nowThe purpose of this study is to determine whether people with MCI (Mild Cognitive Impairment) and healthy comparison subjects differ with respect to their ability to hear soft sounds and how their brain understands and processes sound. The investigators are also evaluating, withi…
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Aug 27, 2026 00:00 UTC
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Breathing workouts may rewire genes in arthritis patients
Knowledge-focused Recruiting nowThe goal of this observational study is to examine the effects of traditional respiratory rehabilitation and respiratory muscle strengthening training added to this program at the genetic level in in patients with rheumatoid arthritis-associated interstitial lung disease. The mai…
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Can a light sensor replace a catheter to measure abdominal pressure in babies?
Knowledge-focused CompletedThe goal of this clinical trial is to learn more about intestinal regional oxygen saturation measurements made with near-infrared spectroscopy and bladder pressure measurements in infants without risk of intraabdominal hypertension. The main question it aims to answer is if - in …
Sponsor: University Children's Hospital, Zurich • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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How long do red blood cells live? new study uses biotin to find out
Knowledge-focused Recruiting nowBackground: Sickle cell disease (SCD) is an inherited disorder of the blood. SCD causes red blood cells (RBCs) to die early. This can lead to a shortage of healthy cells. SCD and other blood disorders can be managed with drugs or cured with a bone marrow transplant. Researchers …
Early phase 1 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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New study: shorter numbing agent may get knee replacement patients moving faster
Symptom relief OngoingPrilocaine numbs you for a shorter time, allowing you to regain movement quicker, which helps you recover faster, start rehab sooner, and feel more satisfied with your treatment overall.
Phase 4 • Sponsor: National University Hospital, Singapore • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Shocking the pelvic floor back to strength: new combo therapy tested
Symptom relief CompletedThis research will determine 1) whether the very weak pelvic floor can be improved with surface electromyography (s-EMG)-triggered electrostimulation added to pelvic floor muscle training and 2) whether sEMG-triggered electrostimulation added to pelvic floor muscle training can r…
Sponsor: Azienda Unita Sanitaria Locale di Piacenza • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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New ankle test may slash re-injury risk for athletes after ligament surgery
Knowledge-focused Recruiting nowAnkle sprain is one of the most common pathologies in the general population (between 2.1 and 3.2 per 1000 patients per year). Nearly 40% of patients will develop chronic instability in the year following the sprain. We also know that a premature return to sport is a risk factor …
Sponsor: Clinique du Sport, Bordeaux Mérignac • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Heart clot registry aims to prevent strokes in thousands
Knowledge-focused Recruiting nowLeft Ventricular Thrombus (LVT) is a blood clot that can develop in a poorly functioning heart. In around 1 in 6 patients who have had a heart attack or diagnosed with heart failure tend to develop blood clots in their main heart chamber. Having a blot clot in the main heart cha…
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Brain surgery breakthrough? scientists decode how electrical mapping affects the brain
Knowledge-focused By invitation onlyElectrocortical stimulation (ECS) mapping is a procedure used during brain surgeries, for example when treating diseases like epilepsy or when removing brain tumors. ECS mapping helps surgeons locate areas of the cerebral cortex (the outer part of the brain) that are important fo…
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Ultrasound may help super obese moms get safer spinal anesthesia
Symptom relief CompletedThis study will investigate whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the sitting position in super obese pregnant women with BMI ≥ 50 who will undergo elective cesarean section. The primary objecti…
Sponsor: Karaman Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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New MRI study hopes to unlock clues to brain recovery after cardiac arrest
Knowledge-focused Recruiting nowThe goal of this observational study is to determine whether specific advanced MRI measures are associated with functional outcomes in patients who are comatose after cardiac arrest. The main question\[s\] it aims to answer are: Aim 1: Determine if stimulus-based functional MRI …
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Which nerve block eases back surgery pain best?
Symptom relief OngoingThis study aims to compare the analgesic efficacy of quadratus lumborum block (QLB) and retrolaminar block (RLB) in patients undergoing lumbar disc herniation surgery. Both regional anesthesia techniques are increasingly used for postoperative pain management, but there is limite…
Sponsor: Kocaeli University • Aim: Symptom relief
Last updated Jun 26, 2026 16:51 UTC
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New study to track Real-World results of HIFU for prostate cancer
Knowledge-focused Recruiting nowMany reports of clinical outcomes following treatment of localized prostate cancer suffer from lack of prospective long-term data using objective and validated outcome instruments. The purpose of this research database is to prospectively collect data to assess treatment related …
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Ancient meets modern: can herbs and acupuncture heal burns faster?
Symptom relief CompletedTo explore the effectiveness of TCM interventional treatment in shortening the recovery time and improving accompanying symptoms of burns and scalds. A single-center, randomized control crossover trial will compare TCM intervention to routine western medicine intervention.
Sponsor: China Medical University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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New stimulation pattern may boost leg power in neurological patients
Symptom relief CompletedTo determine whether Spatially Distributed Sequential Functional Electrical Stimulation is more effective than Standard Electrical Stimulation During Functional Electrical Stimulation in Upper Motor Neuron Patients
Sponsor: UGECAM Rhône-Alpes • Aim: Symptom relief
Last updated Jun 26, 2026 19:03 UTC
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Liver size swings may throw off cancer radiation accuracy
Knowledge-focused Recruiting nowStandard planning constraints for liver SBRT incorporate strict dose-volume limits for normal liver parenchyma to minimize the risk of radiation-induced liver disease. The presence of diurnal and fasting/fed variations in liver volume therefore carry substantial potential for int…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New study aims to ease the burden on parents caring for kids with tracheostomies at home
Symptom relief By invitation onlyThe goal of this trial is to advance the understanding of how to best support caregivers of children with tracheostomies who are caring for their child at home. The main questions it aims to answer are: * What are the best ways to support caregivers post-discharge with both medi…
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC