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127005 trials found · Page 4839 of 6351
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New drug duo aims to slow muscle decline in rare disease
Disease control Recruiting nowTo evaluate the efficacy of Pozelimab/Cemdisiran combination therapy in patients with sIBM
Early phase 1 • Sponsor: Austin Neuromuscular Center • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Simple sponge speeds up tooth extraction recovery, study finds
Symptom relief CompletedTooth extraction is a common dental procedure, where hemostasis is crucial for patient recovery. This study evaluates the effectiveness of hemostatic sponges in controlling bleeding and promoting postoperative healing.
Sponsor: Universidad Nacional de Caaguazu • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Muffin miracle? banana flour shows promise for hypertension
Disease control CompletedThis study evaluated the effects of raw banana flour (RBF)-enriched muffins on hypertensive patients in Lahore, Pakistan. A total of 34 patients were divided into three groups: a control group and two intervention groups receiving muffins with 35% (C1) or 40% (C2) RBF for 10 week…
Sponsor: University of Lahore • Aim: Disease control
Last updated Jun 26, 2026 14:05 UTC
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New hope for rare blood cancers? early trial begins
Disease control OngoingThis study is being conducted to assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 in Participants With Myeloproliferative Neoplasms.
Phase 1 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Could weak legs be making it hard to breathe? new study investigates
Knowledge-focused Recruiting nowDyspnea (i.e. breathlessness) and exercise intolerance are common symptoms for patients with interstitial lung disease (ILD), yet it is not known why. It has been suggested that muscle dysfunction may contribute to dyspnea and exercise intolerance in ILD. Our study aims to: i) ex…
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Can reiki ease cancer pain? small study says maybe
Symptom relief CompletedThe purpose of this research is to investigate the delivery of Reiki to integrative oncology patients and assess its potential for improving cancer-related symptoms in this population.
Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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New Clot-Busting device tested in hong kong
Disease control CompletedThe JETi Hong Kong PMS is a single-arm, multicenter study to collect real-world data on the safety, performance, and clinical benefits of the JETi System for the treatment of acute and subacute thrombosis in the peripheral vasculature. This is a post-market study that will regist…
Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Virtual Mind-Body skills may ease chronic pain for rural veterans
Symptom relief CompletedThis project addresses the significant challenge of providing evidence-based non-pharmacologic pain management to rural-dwelling Veterans in the VA healthcare system who have chronic pain. For this preparatory phase (UG3), the investigators will conduct a single-arm pilot study o…
Sponsor: Minneapolis Veterans Affairs Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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2000 volunteers needed to help spot lung cancer earlier
Knowledge-focused Recruiting nowThis is an observational study designed to determine the optimal combination of biomarkers and clinical data for the early detection, confirmation, and better treatment of lung cancer including minimizing recurrence.
Sponsor: Maverix Medical • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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New study aims to decode deadly heart shock using simple blood and urine tests
Knowledge-focused Recruiting nowThe goal of this observational study is to learn whether information collected during routine hospital care, together with blood and urine samples, can help doctors better identify different types of cardiogenic shock and better predict outcomes in adults hospitalized with acute …
Sponsor: University Heart Center Freiburg - Bad Krozingen • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Which choking rescue works best? mannequin study puts devices to the test
Knowledge-focused CompletedWHY IS THIS STUDY BEING DONE? Little is known about the best treatment for choking. New airway clearance devices like LifeVac© and Dechoker© are being sold to help a choking person. Researchers do not know how well they work compared to other techniques like abdominal thrusts or …
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Simple finger sweep vs balloon: which gets labor started better?
Disease control Recruiting nowThe goal of this interventional study is to evaluate the effectiveness of membrane stripping in cervical ripening compared to double balloon catheter induction. The study population consists of women undergoing labor induction. The main questions it aims to answer are: 1. Is m…
Sponsor: Meir Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Shoulder surgery showdown: to cut or not to cut a chest muscle?
Symptom relief Recruiting nowThe goal of this clinical trial is to assess if concomitant open pectoralis minor release would improve pain and outcomes after Reverse Shoulder Arthroplasty (RSA). The main questions it aims to answer are: * whether releasing the pectoralis minor prophylactically could have bet…
Sponsor: Emory University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New tool aims to empower pregnant women in HIV prevention choices
Prevention CompletedPurpose: The overall objective of this pilot study is to evaluate the feasibility, acceptability, and appropriateness of a shared decision-making (SDM) intervention to support personally appropriate decision making about PrEP use during pregnancy and breastfeeding. Participants:…
Sponsor: University of North Carolina, Chapel Hill • Aim: Prevention
Last updated Jun 27, 2026 09:01 UTC
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New app and therapy aim to keep pregnant women on opioid treatment
Disease control CompletedThis study involves testing how useful a technology-enhanced intervention is for pregnant people prescribed buprenorphine for the management of opioid use disorder. The intervention being studied is a brief therapy protocol and a mobile application. Participation involves four 60…
Early phase 1 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New artificial disc offers hope for chronic neck pain sufferers
Disease control Recruiting nowThis is a real world data collection observational study at a single site. There are both prospective and retrospective cohorts. The study will examine the safety and effectiveness of the Synergy cervical disc system in patients with degenerative cervical disc disease.
Sponsor: Synergy Spine Solutions • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New brain scan could reveal hidden signs of long COVID
Knowledge-focused CompletedThe goal of this study is to evaluate the safety of using the \[5-cyano-N-(4-(4-\[11C\]Methylpiperazin-1-yl)-2-(Piperidin-1-yl)Phenyl)Furan-2-carboxamide\] (\[11C\]CPPC) radiotracer in positron emission tomography (PET) imaging of people with history of COVID-19 infection, with a…
Early phase 1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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New stroke drug shows promise in early safety trial
Disease control CompletedThis study is a multi-center, randomized, double-blind, double-dummy, placebo-controlled, single dose escalation study aimed at evaluating the overall safety, tolerability, and preliminary efficacy of HRS-7450 in patients with acute ischemic stroke.
Phase 1 • Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New program trains diverse students to tackle mental health gaps
Knowledge-focused By invitation onlyThe investigators propose a multi-step approach to improve access to mental health care. The plan focuses on three goals: increasing diversity in the mental health workforce, bringing more expertise into the community, and strengthening the community's ability to address the fact…
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Smart pain monitor may reduce opioid use in endometriosis surgery
Symptom relief CompletedAdequate analgesia in the perioperative setting is one of the most important pillars of anesthesiology. It is generally understood that poorly managed acute postoperative pain correlates with increased morbidity, prolonged recovery periods, extended opioid utilization, and serves…
Sponsor: Prof Urs Zingg • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC