New hope for rare blood cancers? early trial begins

NCT ID NCT06313593

Recruiting now Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new drug called INCB160058 in adults with myeloproliferative neoplasms, a group of rare blood cancers. The main goal is to check the drug's safety and how the body processes it. About 186 participants will receive the drug to find the right dose and watch for side effects.

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Conditions

The condition(s) this trial relates to.

acquired polycythemia vera essential thrombocythemia myelofibrosis Myeloproliferative Disorders myeloproliferative neoplasm primary myelofibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYELOPROLIFERATIVE NEOPLASMS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aou Policlinico S. Orsola-Malpighi
NOT_YET_RECRUITING

Bologna, 40138, Italy
Azienda Ospedaliero-Universitaria Careggi (Aouc)
NOT_YET_RECRUITING

Florence, 50134, Italy
Cornell Medical Center
RECRUITING

New York, New York, 10021, United States
Fondazione Irccs Ca Granda Ospedale Maggiore
NOT_YET_RECRUITING

Milan, 20122, Italy
Genesiscare Oxford
NOT_YET_RECRUITING

Oxford, OX4 6LB, United Kingdom
Guys and St Thomas Nhs Foundation Trust
NOT_YET_RECRUITING

London, SE1 9RT, United Kingdom
Haukeland University Hospital
RECRUITING

Bergen, N-5021, Norway
Hopital Maisonneuve-Rosemont, Montreal, Qc
RECRUITING

Montreal, Quebec, H1T 2M4, Canada
Hospital Saint Louis
RECRUITING

Paris, 75010, France
Icahn School of Medicine At Mount Sinai
RECRUITING

New York, New York, 10029, United States
Inselspital - Universitaetsspital Bern
RECRUITING

Bern, 03010, Switzerland
Institut Gustave Roussy
RECRUITING

Villejuif, 94805, France
McGill University Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Md Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
Oregon Health & Science University
RECRUITING

Portland, Oregon, 97239, United States
Oslo University Hospital
RECRUITING

Oslo, 00379, Norway
Princess Margaret Cancer Center
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Sloan Kettering Institute For Cancer Research
RECRUITING

New York, New York, 10065, United States
Stanford University
RECRUITING

Palo Alto, California, 94304, United States
The University of Alabama At Birmingham
RECRUITING

Birmingham, Alabama, 35249, United States
The University of Kansas Cancer Center Kucc University of Kansas Clinical Research Center
RECRUITING

Fairway, Kansas, 66205, United States
Universitatsklinikum Essen
NOT_YET_RECRUITING

Essen, 45147, Germany
Universitatsklinikum Halle (Saale)
RECRUITING

Halle, 06120, Germany
Universitatsspital Zurich
RECRUITING

Zurich, 08091, Switzerland
University Medical Center Rwth Aachen
RECRUITING

Aachen, D-52074, Germany
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109-5008, United States
University of Pennsylvania Health System
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Vanderbilt-Ingram Cancer Center
RECRUITING

Nashville, Tennessee, 37232, United States

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