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116076 trials found · Page 4823 of 5804
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Balloon implant for prostate cancer passes Long-Term safety check
Disease control OngoingLong-Term Prospective Post Marketing Clinical Follow Up for Evaluation of the BioProtect Balloon Implant™ System
Sponsor: BioProtect • Aim: Disease control
Last updated Jun 26, 2026 18:51 UTC
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New score could save lives by predicting bleeding deaths in cirrhosis patients
Knowledge-focused Recruiting nowAcute gastrointestinal bleeding is potentially lethal in liver cirrhosis. Accurate assessment of prognosis is critical in a timely fashion. A novel model, CAGIB score, has been developed based on our Chinese multicenter retrospective study. Now, a prospective, international multi…
Sponsor: Xingshun Qi • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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MRI and AI join forces to track spine disease activity
Knowledge-focused Recruiting nowThis study aims to further improve and expand the WB-MRI imaging evaluation cohort of axSpA patients to complete dynamic follow-up and condition assessment. Based on the WB-MRI features, the association of WB-MRI signs with disease activity, inflammation, and structural damage wi…
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Does anesthesia flow rate affect inflammation in obesity surgery?
Knowledge-focused CompletedThis retrospective observational study aimed to compare the effects of low-flow and standard-flow sevoflurane anesthesia on perioperative inflammatory responses in patients undergoing laparoscopic sleeve gastrectomy for obesity. Data were obtained from the anesthesia and laborato…
Sponsor: Adana City Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Can shedding pounds sharpen your mind? huge study investigates
Knowledge-focused ENROLLING_BY_INVITATIONStudy is designed to screen psychological cognitive baseline and retention/improvement after weight loss surgery.
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Warm showers during labor: a soothing strategy for pain relief?
Symptom relief CompletedThe use of non-pharmacological methods in labor pain is very important in order to improve the birth process, increase comfort and provide relaxation. The role of midwives, acting as patient advocate is to maintain comfort throughout the birth process. In order to do this, she sh…
Phase: NA • Sponsor: Gulhane School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Could a simple Add-On drug make C-Section recovery smoother?
Symptom relief CompletedThe study hypothesizes that addition of dexmedetomidine to bupivacaine either in spinal anesthesia or TAP block is more effective and provide better ObsQor-11score than bupivacaine alone. Also, Dexmedetomidine in TAP block might provide a longer pain free time in comparison to in…
Phase: PHASE4 • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Warm foot bath may ease pain and anxiety after surgery
Symptom relief CompletedThis study was planned and will conducted to determine the effect of hot foot bath on pain, anxiety, sleep and comfort levels in patients undergoing laparoscopic cholecystectomy. Research hypotheses H1: A hot foot bath reduces postoperative pain in patients undergoing laparoscop…
Phase: NA • Sponsor: Dilek GÜRÇAYIR • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Blood test scores may reveal heart attack risk
Knowledge-focused CompletedIt is well known that malnutrition is a prognostic risk factor in chronic heart failure (CHF). Weight loss and the development of cardiac cachexia are associated with poor prognosis in CHF. However, objective indices such as the Prognostic Nutrition Index (PNI) and Controlling Nu…
Sponsor: Muğla Sıtkı Koçman University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Hands-free pump aims to boost lactation for black mothers in the NICU
Symptom relief CompletedRacial disparities result in Black infants in the neonatal intensive care unit (NICU) receiving less breast milk (BM) than White and Hispanic infants.1 BM improves infant health yet mothers of critically ill infants produce insufficient amounts to provide these benefits which is …
Phase: NA • Sponsor: University of Florida • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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New tool could spot tough pneumonia early
Knowledge-focused CompletedThis is a single-center, non-profit observational study with two sequential phases: an initial retrospective phase followed by a prospective phase. Patients were enrolled during two consecutive, non-overlapping periods. The primary objective of the study is to derive a clinical …
Sponsor: Azienda Ospedaliero-Universitaria Careggi • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Can a squirt of heart medicine boost bypass success?
Knowledge-focused CompletedForty-six consecutive patients undergoing elective primary coronary artery bypass grafting were enrolled. After the left IMA was harvested, free flow was measured under controlled hemodynamic conditions before any intervention (flow 1) and at a mean of 12.5 minutes after the topi…
Phase: PHASE3 • Sponsor: Damascus University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Spinal tumor surgery under the microscope: what really happens?
Knowledge-focused OngoingIntradurale spinal tumors are rare neoplastic lesions that involve the spinal cord and surrounding structures and may cause neurological symptoms such as pain, motor deficits, sensory disturbances, and sphincter dysfunction. Surgical resection is often the primary treatment when …
Sponsor: Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New study tracks Real-World care for sinonasal and Skull-Base tumours
Knowledge-focused Recruiting nowThis observational prospective clinical study aims to describe the epidemiology, management and outcome of patients with sinonasal and skull-base pathology (tumours and diseases with malignant clinical characteristics) in a tertiary otorhinolaryngology referral centre. The main q…
Sponsor: University Medical Centre Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Which Heart-Lung machine is safer for your brain?
Knowledge-focused CompletedThe aim of the present study is to investigate the protective effect of minimal invasive versus the conventional extracorporeal circulation on tissue homeostasis as evidenced by the preservation of tissue metabolism and cerebral perfusion.
Phase: NA • Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Digital twin predicts muscle gains: a new era for personalized fitness?
Knowledge-focused CompletedBackground: Muscular strength training interventions have long been a cornerstone in the prevention, non-surgical management and rehabilitation of the entire spectrum of musculoskeletal injuries and diseases. The key goal of strength training, especially during rehabilitation, is…
Phase: NA • Sponsor: Silvio Lorenzetti • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Healing hands: therapeutic touch eases anxiety and improves sleep in hospitalized seniors
Symptom relief CompletedThe aim of this study is to determine the effect of the therapeutic touch applied to the sleep patterns of individuals aged 65-85 years with chronic diseases who are treated in the Neurology Intensive Care Unit of Ankara City Hospital, taking into account the circadian cycle.The …
Phase: NA • Sponsor: KTO Karatay University • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Your iPhone could help monitor psoriasis: new study tests smartphone tracking
Knowledge-focused OngoingThe purpose of this study is to understand variation in the symptoms of psoriasis and psoriatic arthritis using simple, scalable smartphone-based measurements. This study uses an iPhone app to record these symptoms through questionnaires and sensors.
Sponsor: Sage Bionetworks • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Dental implant infection showdown: which cleaning method wins?
Disease control OngoingTwo groups are aimed at being investigated in three centers (CICOM, Clinica Branemark and Clinica Joan Pi) * Test group: Group electrolytic approach (EA): Mechanical detoxification using curettes + NiTi brushes + EA (GalvoSurge) during 2 minutes * Control group: Group hydrogen p…
Phase: NA • Sponsor: Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Could probiotic pasta help fight obesity?
Disease control CompletedThis study aims to investigate the effects of daily consumption for 4 weeks of a probiotic durum wheat pasta vs a conventional durum wheat pasta without probiotics on fasting metabolic parameters and inflammatory status, on gut permeability and functionality, on daily energy inta…
Phase: NA • Sponsor: Federico II University • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC