Could pectin and calcium silicate beat root canal infections?

NCT ID NCT07423663

Ongoing Disease control Sponsor: Suez Canal University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests whether calcium silicate and pectin, placed inside the tooth, can kill bacteria better than standard calcium hydroxide in root canals of dead teeth with abscesses. 63 adults with a single infected premolar will receive one of the three medications. The study measures changes in the types of bacteria present before and after treatment to see which works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Calcium silicate, pectin, and calcium hydroxide (as intracanal medications)
What this could lead to: If successful, this could point toward better, less resistance-prone disinfectants for root canal treatments.
What could go wrong: This is a very early, small trial (63 people) testing only one type of tooth. Results may not apply broadly, and the medications may not outperform standard treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASYMPTOMATIC APICAL PERIODONTITIS

Contacts and locations

Locations

Suez Canal University

Ismailia, Ismailia Governorate, 41511, Egypt

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