Could pectin and calcium silicate beat root canal infections?
NCT ID NCT07423663
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests whether calcium silicate and pectin, placed inside the tooth, can kill bacteria better than standard calcium hydroxide in root canals of dead teeth with abscesses. 63 adults with a single infected premolar will receive one of the three medications. The study measures changes in the types of bacteria present before and after treatment to see which works best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Calcium silicate, pectin, and calcium hydroxide (as intracanal medications)
What this could lead to
If successful, this could point toward better, less resistance-prone disinfectants for root canal treatments.
What could go wrong
This is a very early, small trial (63 people) testing only one type of tooth. Results may not apply broadly, and the medications may not outperform standard treatments.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Suez Canal University
Ismailia, Ismailia Governorate, 41511, Egypt