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116076 trials found · Page 4822 of 5804
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New study tests if video laryngoscopy makes tracheostomy safer
Knowledge-focused Recruiting nowWhen preparing an ICU patient for percutaneous dilational tracheostomy, correct positioning of the endotracheal tube is important. During the procedure, it is possible to puncture the cuff. Tracheal tube cuff puncture can lead to failure of ventilation, loss of positive end-expir…
Phase: NA • Sponsor: Hospital Clinico Universitario de Santiago • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:24 UTC
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Infection risk after aortic repair: what the data show
Knowledge-focused TerminatedThe infection rate of thoracic endovascular aortic repair (TEVAR) is unknown due to a lack of epidemiological data. The rate currently available comes from researches conducted decades ago, when open surgery was the standard of care. Because of the potentially fatal consequences …
Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Bismuth combo therapy for stomach bug under review
Knowledge-focused CompletedBismuth-containing quadruple therapy was recommended as a first-line treatment for Helicobacter pylori infection. This study aimed to compare real-world outcomes of various bismuth-containging quadruple regimens and identify factors influencing treatment failure. A multicenter re…
Sponsor: Yueyue Li • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:22 UTC
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New study reveals hidden causes of bowel blockage in Surgery-Free patients
Knowledge-focused CompletedSmall bowel obstruction (SBO) is a surgical emergency in which the passage of intestinal contents is prevented due to mechanical obstruction of small intestine. It accounts for almost 50% of all emergency laparotomies with significant in-hospital morbidity and costs. SBO has know…
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:43 UTC
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MRI and AI join forces to track spine disease activity
Knowledge-focused Recruiting nowThis study aims to further improve and expand the WB-MRI imaging evaluation cohort of axSpA patients to complete dynamic follow-up and condition assessment. Based on the WB-MRI features, the association of WB-MRI signs with disease activity, inflammation, and structural damage wi…
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Warm showers during labor: a soothing strategy for pain relief?
Symptom relief CompletedThe use of non-pharmacological methods in labor pain is very important in order to improve the birth process, increase comfort and provide relaxation. The role of midwives, acting as patient advocate is to maintain comfort throughout the birth process. In order to do this, she sh…
Phase: NA • Sponsor: Gulhane School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Is this constipation pill safe for pregnant women? new study investigates
Knowledge-focused OngoingThis study will collect information on pregnant women diagnosed with constipation from the two large health care insurance claims records. It will include the following groups: * Those who took prucalopride. * Those who took other medicines for constipation. * Those who did not…
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New registry aims to improve bile duct stone removal
Knowledge-focused OngoingThe Percutaneous Cholangiopancreatoscopy (PCPS) registry is an observational, multicentric, prospective, and retrospective registry of patients undergoing the percutaneous cholangiopancreatoscopy procedure at sites across the United States. In the retrospective component of the s…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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New gel could ease pain after sinus surgery
Symptom relief CompletedPostoperative care of patients undergoing endoscopic sinus surgery (ESS) is important both to minimize discomfort for the patients and to obtain the optimal long-term outcomes. Postoperative sinonasal cavity debridement has been advocated to prevent potential synechiae and sinus …
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Can a squirt of heart medicine boost bypass success?
Knowledge-focused CompletedForty-six consecutive patients undergoing elective primary coronary artery bypass grafting were enrolled. After the left IMA was harvested, free flow was measured under controlled hemodynamic conditions before any intervention (flow 1) and at a mean of 12.5 minutes after the topi…
Phase: PHASE3 • Sponsor: Damascus University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Spinal tumor surgery under the microscope: what really happens?
Knowledge-focused OngoingIntradurale spinal tumors are rare neoplastic lesions that involve the spinal cord and surrounding structures and may cause neurological symptoms such as pain, motor deficits, sensory disturbances, and sphincter dysfunction. Surgical resection is often the primary treatment when …
Sponsor: Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Tongue position after jaw surgery may determine Long-Term success
Knowledge-focused CompletedThe anterior gap is defined by a lack of contact between the upper and lower dental arches. It is mainly due to the persistence of infantile swallowing during and after childhood, i.e. interposition of the tongue between the two dental arches. Patients presenting with an anteri…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Shock therapy vs. pills: which depression treatment wins on cost?
Knowledge-focused OngoingProspective observational cohort study to determine cost-effectiveness of ECT compared to medication in the treatment of major depressive disorder (MDD) in the Netherlands.
Sponsor: Radboud University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Massive diabetes study launches to uncover Long-Term trends
Knowledge-focused Recruiting nowThe aim of the China Diabetes Type 1 Study (CD1S) is to conduct a nationwide type 1 diabetes (T1D) registry study in patients with T1D and in pediatric adolescent patients with diabetes who had an age of onset \<= 20 years. CD1S compromises a retrospective study enrolling inpati…
Sponsor: Second Xiangya Hospital of Central South University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New study tests better stitching to prevent leaks after weight-loss surgery
Symptom relief CompletedThis prospective comparative cohort study was conducted in accordance with the Declaration of Helsinki and approved by the Ethical Committee of the Medical Research Institute. All consecutive patients undergoing laparoscopic sleeve gastrectomy (LSG) between January 2022 and June …
Phase: NA • Sponsor: Al-Kindy Teaching Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Which Heart-Lung machine is safer for your brain?
Knowledge-focused CompletedThe aim of the present study is to investigate the protective effect of minimal invasive versus the conventional extracorporeal circulation on tissue homeostasis as evidenced by the preservation of tissue metabolism and cerebral perfusion.
Phase: NA • Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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AI model could spot hidden blood clot risk in ICU patients
Knowledge-focused CompletedVenous thromboembolism remains a leading cause of preventable mortality in intensive care unit (ICU) patients. Existing risk-stratification tools were developed in general medical populations and lack ICU-specific predictors. This study was to develop and validate an interpretabl…
Sponsor: Beijing Tsinghua Chang Gung Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Skip the tacks? study tests Pain-Free hernia repair
Symptom relief CompletedThe role of mesh fixation in laparoscopic totally extraperitoneal (TEP) inguinal hernia repair remains controversial. While fixation may increase postoperative pain, concerns about recurrence in larger defects prevent its complete abandonment. This study aimed to compare absorbab…
Phase: NA • Sponsor: Antalya Health Sciences University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Dialysis itch relief: could a simple education program be the answer?
Symptom relief CompletedThis study evaluates the effect of a Health Belief Model (HBM)-based educational intervention on pruritus severity and pruritus-related quality of life (QoL) in hemodialysis patients. The cluster-randomized controlled trial includes hemodialysis patients allocated to an intervent…
Phase: NA • Sponsor: Ege University • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Could a simple blood test spot eye damage from diabetes?
Knowledge-focused Recruiting nowDiabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessel…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC