Old drug, new trick? metformin may help seniors regain muscle
NCT ID NCT06185179
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage study tests whether metformin, a widely used diabetes medication, can improve muscle regrowth in older adults after a period of inactivity (like bed rest). Fifty volunteers aged 60 and older will receive either metformin or a placebo during recovery. The goal is to see if metformin helps the thigh muscle recover more fully, potentially reducing fall risk and loss of independence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Metformin (a common diabetes drug)
- What this could lead to
- If it works, this could point toward a simple, affordable way to help older adults regain muscle strength after periods of inactivity.
- What could go wrong
- This is a very early, small trial (50 people) testing a short-term effect. Metformin is generally safe but may cause stomach upset; it's not proven yet for muscle recovery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MUSCLE ATROPHY OR WEAKNESS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.