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127005 trials found · Page 4712 of 6351
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New study reveals key infection risks for intestinal failure patients
Knowledge-focused CompletedThis retrospective cohort study aims to identify risk factors for catheter-related bloodstream infections (CRBSIs) in hospitalized patients with intestinal failure (IF), including all subtypes (Types I-III). The study included 321 patients with 9,365 catheter-days. Multivariate l…
Sponsor: Jinling Hospital, China • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:14 UTC
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Can a simple ultrasound spot miscarriage risk early?
Knowledge-focused CompletedThe synthesis of progesterone by corpus luteum is extremely important for the maintenance of normal pregnancy in the first seven weeks. Similarly, the production of progesterone by the placental syncytiotrophoblast increases progressively during the first weeks of gestation, so t…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can two diabetes drugs save kidneys after cancer surgery?
Disease control Stopped earlyThe goal of this clinical trial is to evaluate whether Finerenone and Empagliflozin, either alone or in combination, can delay the progression of renal function decline in patients at high risk for chronic kidney disease (CKD) following radical nephrectomy for renal cell carcinom…
Phase 2 • Sponsor: Jinling Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Deep cleaning study targets gum Disease's toughest pockets
Disease control OngoingThis study will retrospectively evaluate the outcomes of scaling and root planing over a two year time period. The study will focus specifically on the effectiveness of SRP in pockets with an initial pre-treatment pocket probing depth of ≥ 5 mm and ≤ 8 mm. The study will also exa…
Sponsor: Texas A&M University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Global heart valve study seeks to uncover hidden differences in patients before treatment
Knowledge-focused By invitation onlyThe aim of the project is to evaluate demographic, clinical, and laboratory variations in patients with aortic stenosis treated with TAVI in different countries. Moreover, the study will evaluate interpopulation differences in aortic root anatomy based on computed tomography anal…
Sponsor: Poznan University of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Botox and laser combo tested for burn scars
Symptom relief CompletedThe current study aimed to evaluate the effectiveness of fractional laser treatment alone and fractional laser combined with botulinum toxin A, delivered either through injections or topical application fractional laser-assisted drug delivery (FLADD) in hypertrophic burn scar
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New pain combo cuts opioid need after bariatric surgery
Symptom relief CompletedAnalgesic Efficacy of adding different doses of dexmedetomidine as adjuvants with bupivacaine vs. bupivacaine only in ultrasound-guided erector spinae plane block in morbidly obese patients undergoing Laparoscopic Bariatric surgery. A RANDOMIZED CONTROLLED DOUBLE BLINDED STUDY.
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Laser or toothpaste: which zaps tooth pain best?
Symptom relief CompletedDentinal hypersensitivity is a common clinical condition characterized by short, sharp pain arising from exposed dentin in response to thermal, tactile, or evaporative stimuli. It can significantly affect oral health-related quality of life and routine dental care. Various treatm…
Sponsor: King Khalid University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Nurse-led emergency care may cut repeat hospital visits
Knowledge-focused CompletedEmergency departments are facing increasing overload, exacerbated by difficulties in accessing primary care. This saturation impacts the fluidity of care pathways and the quality of care. A major challenge is the high rate of short-term repeat visits, which increases the workloa…
Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Simple stretches may ease Post-Injury knee stiffness
Symptom relief CompletedThe study was conducted to compare the effects of hold-relax and muscle energy technique on pain, range of motion an lower extremity function in patients with post-traumatic knee stiffness.
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Eye lens rotation study aims to sharpen cataract surgery outcomes
Knowledge-focused Recruiting nowThis prospective comparative cohort study evaluates and compares postoperative rotational stability and time-course dynamics of three commercially available toric intraocular lenses (TECNIS Toric II \[ZCU\], AcrySof IQ Toric, and AT TORBI 709M) after phacoemulsification cataract …
Sponsor: Jin Yang • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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New training aims to help parents prevent arm stiffness in newborns
Knowledge-focused Recruiting nowThe brachial plexus is a network of nerves that exit the spinal cord from the C5-T1 nerve roots and provide all motor and sensory function to the arm from the shoulder to the fingers. Injury to the brachial plexus due to traction forces during labor and/or delivery causing the ne…
Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Needle therapy showdown: which dose best eases stubborn neck pain?
Symptom relief CompletedNeck pain is a common health problem in the general population. Approximately 71% of adults experience neck pain at some point in their lives, and its annual prevalence ranges between 30-50% in both the general and working populations. Although neck pain often resolves spontaneou…
Sponsor: Istanbul Medeniyet University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New combo may ease pain after gallbladder removal
Symptom relief CompletedLaparoscopic cholecystectomy (LC) is one of the commonly performed surgical procedures associated with a moderate degree of postoperative pain especially on the 1st postoperative day. Adequate postoperative analgesia allows early patient ambulation, decreases analgesic requiremen…
Phase 4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Two-Minute wait after spinal injection may prevent blood pressure drops in elderly
Knowledge-focused CompletedBackground: Geriatric patients undergoing femoral neck of fracture (FNOF) repair are highly susceptible to spinal anesthesia-induced hypotension. This study examines whether a two-minute delayed supine position after spinal injection reduces this risk. Methods: Ninety patients ag…
Phase 2 • Sponsor: Sohar Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Spine screw system under Long-Term review
Knowledge-focused By invitation onlyThe purpose of this observational, multi-center, ambispective, serial case study is to collect real-world patient outcomes that characterize the long-term safety and effectiveness of the SurGenTec ION 3D® Facet Screw System in a cervical spine and a lumbar spine application.
Sponsor: SurGenTec LLC • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Brain zaps for pain and fatigue: a quick fix?
Symptom relief Stopped earlyFunctional and Affective Effects of a brief tDCS Intervention in Fibromyalgia and Chronic Fatigue Syndrome Fibromyalgia (FM) and chronic fatigue syndrome (CFS) are characterized by persistent, multidimensional symptoms arising from complex brain-body interactions that impair func…
Sponsor: Hospital Donostia • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Stress ball may ease anxiety during hand surgery, study finds
Symptom relief CompletedPreoperative anxiety begins from the decision-making of surgery to entering the operating room and may intensify as the surgery date approaches. Anxiety not only causes physiological effects but also psychological impacts, leading to negative outcomes for postoperative recovery. …
Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Gum disease inflammation link explored in new study
Knowledge-focused CompletedThis study aims to investigate the relationship between NLRP3 inflammasome activation and different stages of periodontitis, with a focus on its association with inflammaging. Periodontitis is a chronic inflammatory disease affecting the supporting tissues of the teeth, and aging…
Sponsor: Misr University for Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Ancient moxibustion therapy tested for nocturia relief
Symptom relief Recruiting nowNocturia, the interruption of sleep due to nighttime voiding, severely compromises quality of life, emotional health, and overall well-being when occurring twice or more per night. Given that some patients experience inadequate responses to conventional Western therapies or harbo…
Sponsor: Buddhist Tzu Chi General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC