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127005 trials found · Page 4705 of 6351
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Chilly workouts may alter what you eat, small study suggests
Knowledge-focused CompletedThis study investigated whether exercising in cold environments affects appetite, energy intake, and food preference compared with exercising in thermoneutral conditions. Eleven healthy males completed five laboratory trials as part of a crossover study: a control trial and four …
Sponsor: Coventry University • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Scabies cure rates under the microscope: national study reveals treatment success
Knowledge-focused CompletedMulticentre retrospective, prospective, non-profit, national observational study
Sponsor: Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New light device could replace invasive fluid monitoring in ICUs
Knowledge-focused Recruiting nowProof-of-concept observational study including ICU patients undergoing a PLR maneuver. Local microvasculature will be assessed with the hDOS platform on the brachioradialis muscle, deriving the microvascular blood flow index (BFI) and tissue oxygen saturation (StO2). CO will be a…
Sponsor: Corporacion Parc Tauli • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New C-Section pain protocol shows promise in reducing severe pain
Symptom relief CompletedInadequate pain relief remains a challenge after Cesarean section (CS) and may significantly impair postoperative recovery. A recent Danish single-center study (n=100) revealed that 66% of elective CS patients experienced severe pain (NRS ≥ 7) during the first 24 hours, with the …
Sponsor: Nordsjaellands Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Heart failure patients get a digital boost: video education trial launches
Knowledge-focused By invitation onlyBackground: Heart Failure (HF) is one of the most prevalent pathologies in Western countries, representing a significant percentage of their healthcare expenditure. Much of the success of specialised programmes for the control and treatment of this pathology is achieved within He…
Sponsor: Maria Jose Santi Cano • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Firefighters at risk: study reveals heat stress weakens balance and strength
Knowledge-focused CompletedThis study will examine the effect of heat stress on factors that influence musculoskeletal injury risk in firefighters. Participants will attend 4 data collection sessions. 1: informed consent, screening, and familiarization. 2: pre-tests (strength, balance, and movement quality…
Sponsor: Louisiana State University Health Sciences Center Shreveport • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Patient voices shape better anesthesia for emergency C-Sections
Knowledge-focused CompletedThis study aims to explore the patients' and providers' perspectives and inform future anesthetic practice for patients undergoing unexpected cesarean delivery (CD) under neuraxial anesthesia (NA). The consideration of patients' concerns, preferences, expectations, and suggestion…
Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Skin cancer surgery pain showdown: four numbing drugs compared in major trial
Symptom relief By invitation onlyTo compare several local anesthetics when used during dermatological surgery.
Phase 4 • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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New therapy program shows promise in reducing suicide risk for dementia caregivers
Symptom relief CompletedThis project aims to adapt, implement, and evaluate a Dialectical Behavior Therapy skills training group intervention for aging adult family caregivers of person with Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) to reduce suicidality. By adapting this m…
Sponsor: Texas Tech University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Sleep lessons may soothe diabetic nerve pain in small trial
Symptom relief CompletedThis randomized controlled study was designed to the effect of sleep hygiene education on sleep quality and quality of life in patients with painful diabetic polyneuropathy The study was conducted between January 2025 and January 2026 with 24 patients diagnosed with painful diabe…
Sponsor: Trakya University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New eye test criteria could speed up diagnosis of vision loss cause
Diagnosis Recruiting nowOptic neuritis is an important cause of acute or subacute visual loss. In clinical practice, optic neuritis must often be distinguished from other optic neuropathies, retinal diseases, anterior-segment or ocular media disorders, non-organic visual loss, and other mimics. The 2022…
Sponsor: First Affiliated Hospital of Guangxi Medical University • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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Simple ankle moves may ease chronic knee pain, study finds
Symptom relief CompletedThe goal of this randomized research study is to investigate the acute effects of ankle exercises on improving knee proprioception and pain in individuals with knee pain, aged 18-70, who receive intervention-based ankle and knee exercises to treat their knee pain. The main questi…
Sponsor: Gaziantep Islam Science and Technology University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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AI dentist shows bias? new study checks if computer diagnosis works for all races
Knowledge-focused Recruiting nowThis study explores how artificial intelligence (AI) can be used in orthodontics, which is the area of dentistry that focuses on correcting jaw and bite problems. AI is a computer technology that can learn from large amounts of data and then make predictions or decisions. It is a…
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Neighborhood helpers aim to break mental health stigma in latino communities
Knowledge-focused Recruiting nowThe goal of this clinical trial is to increase and strengthen connections between Latino/a individuals and mental health services. Through this intervention, the investigators aim to improve mental health literacy, decrease stigma, increase coping skills, and increase mental heal…
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Scientists zap the brain to unlock sleep secrets
Knowledge-focused By invitation onlyThe thalamus plays a key role in supporting sleep and is also a target of therapeutic stimulation. This project investigates when, where, and how electrical stimulation delivered to the thalamus in humans elicits or disrupts sleep oscillations. This research is a first step to be…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Basketball players test three knee treatments in new study
Symptom relief CompletedThis is a randomized RTC study where the KOS-ADLS score of athletes' functionality and the OSTRC score of sports overuse injuries were used as outcomes, which were measured before the start of treatment, 1 hour and 2 weeks after treatment. In this study, 3 forms of intervention w…
Sponsor: University Aleksander Moisiu Durres • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Skin deep: new study probes hidden signals in hidradenitis
Knowledge-focused CompletedThis observational translational study aims to investigate gene and protein expression in lesional and perilesional skin of patients with Hidradenitis Suppurativa (HS) compared to controls. Skin biopsies were collected from 15 HS patients and 15 age- and sex-matched healthy contr…
Sponsor: Trakya University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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AI chatbot aims to ease tough choices for osteoarthritis patients
Knowledge-focused OngoingThe goal of this clinical trial is to assess the use of a generative artificial intelligence large language model chatbot in improving decision making factors in patients with hip and knee osteoarthritis. The main questions it aims to answer are: Does the use of an artificial in…
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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DASH diet put to the test against kidney stones
Disease control Recruiting nowThe true capacity for a healthy diet to improve urinary stone risk factors is not well-defined. The objective of this study is to measure the effect of adopting a healthy dietary pattern on kidney stone disease (KSD) risk. The working hypothesis is that a Dietary Approaches to St…
Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Gum nicotine levels may predict periodontitis treatment success
Knowledge-focused By invitation onlyImpact of nicotine gingival intoxication on the clinical outcomes after periodontitis non surgical treatment
Sponsor: University of Liege • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC