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116076 trials found · Page 4582 of 5804
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Fibromyalgia pain puzzle: researchers sort pain into types
Knowledge-focused CompletedFibromyalgia Syndrome (FMS); is a complex syndrome characterized by many symptoms such as chronic widespread pain, fatigue and sleep disorders, cognitive dysfunctions and psychiatric disorders. It has been stated that there is an urgent need for studies examining the clinicimetri…
Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Does your new lens slip? study probes link between lens position and sight quality
Knowledge-focused CompletedThe goal of this observational study is to assess the effect of intraocular lens (IOL) movement in patients who have undergone Clareon® Vivity® IOL implantation. The main question it aims to answer is: Does an association exist between IOL movement and patient quality of vision?…
Sponsor: East Coast Institute for Research • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Reiki may ease pain and anxiety after colorectal surgery, small study suggests
Symptom relief CompletedReiki touch therapy has been used for many years, especially on pain, anxiety and physiological parameters, and studies have been found to show that it is effective. In a systematic review conducted with Sectio patients, it was determined that reiki reduces pain. In a study condu…
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 26, 2026 18:11 UTC
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Sugar water injection may ease PTSD symptoms
Symptom relief OngoingPTSD is a chronic mental health condition that drastically reduces an individual's quality of life Dextrose injection with a small needle has been used for chronic pain patients and observational results have shown it to be effective in reducing anxiety, brain fog, and depression…
Phase: NA • Sponsor: Dr. Dean Reeves Clinic • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Light therapy may help athletes recover faster
Symptom relief CompletedIntroduction: Photobiomodulation therapy (PBMT) is based on the emission of light ranging from red to near-infrared spectra by different devices based on diode lasers or light-emitting diodes. These devices emitting different wavelengths can increase mitochondrial activity and en…
Phase: NA • Sponsor: Universidade Federal de Sao Carlos • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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No pain pills? study tests Opioid-Free recovery after hernia repair
Symptom relief OngoingThe investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investiga…
Phase: PHASE4 • Sponsor: Clayton Petro • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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ICU brain study seeks safer sedation targets
Knowledge-focused Recruiting nowThe risk associated with arterial hypotension during anesthesia for intensive care sedation has been demonstrated, but the threshold at which consequences for perfusion of one or more organs appear varies according to the mechanism of hypotension, associated abnormalities (HR, ca…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Lupus skin drug trial halted early – only 8 volunteers joined
Disease control TerminatedThe purpose of this study is to learn about the effects, safety and how PF-06823859 is processed in adults with cutaneous lupus erythematosus (CLE) or systemic lupus erythematosus (SLE) showing some skin symptoms. This study is seeking for participants who: * are adults of 18 y…
Phase: PHASE2 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Stanford launches massive study to track oropharyngeal cancer over time
Knowledge-focused Recruiting nowThe purpose of this study is to better understand the natural history of oropharyngeal carcinoma (OPC), with or without an association with the human papilloma virus (HPV). For this study, the investigators plan to collect blood from OPC patients prior to treatment and at six sub…
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Study aims to tame the 'extinction burst' in child behavior therapy
Knowledge-focused Recruiting nowAlthough highly effective, treatments like FCT include extinction, which can have adverse side effects. The extinction burst, an increase in the frequency or intensity of destructive behavior at the start of treatment, is the most common side effect of extinction, and can increas…
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Sound waves could spot gum disease before it's too late
Diagnosis CompletedThe goal of this clinical investigation is evaluation the agreement between the periodontal pocket depth measurement obtained by periodontal probing (gold standard) and the measurement obtained by the ultrasound device
Phase: NA • Sponsor: University Hospital, Tours • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Older adults with HIV may safely switch to a simpler two-drug pill
Disease control CompletedThe study aims at evaluating the maintenance of virologic suppression of dolutegravir/lamivudine (DTG/3TC) fixed dose combination (FDC) at Week 48 post-switch from bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) in participants living with Human Immunodeficiency Vir…
Phase: PHASE3 • Sponsor: ViiV Healthcare • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Could a tiny dose of radiation ease your jaw pain?
Symptom relief Recruiting nowWith this pilot study, the acute side effects and potential pain relieve after radiotherapy (RT) of the temporomandibular joint (TMJ) are prospectively recorded. For this purpose, the symptoms of the jaw joint arthrosis/arthritis are recorded using a symptom-oriented questionnai…
Phase: NA • Sponsor: Medical University of Vienna • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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New injection for kids with lupus shows promise in small study
Disease control CompletedThis study will evaluate the pharmacokinetic characteristics and safety of belimumab subcutaneous (SC) in Chinese pediatric participants with SLE who have completed 48 weeks belimumab Intravenous (IV) treatment in 213560 study (NCT04908865)
Phase: PHASE1 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Can a virtual chat program boost job success for autistic adults?
Knowledge-focused CompletedThis study is aiming to see if it is feasible for the intervention Work Chat to be delivered in a completely online setting to adults with autism spectrum disorder.
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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New study aims to improve how we assess motor skills in kids with brain injuries
Knowledge-focused Recruiting nowThe overall goal of this study is to develop and improve assessment methods for children with and without perinatal arterial ischemic stroke (PAS)/hemiparetic cerebral palsy (HCP). The focus is on behaviors of the arms and hands and includes other domains of child development lik…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Massive study of 2 million AF patients reveals Real-World impact of blood thinners
Knowledge-focused CompletedThe purpose of this study is to look at how many patients with AF had strokes, major bleeding and death in both people who had and had not taken any oral anticoagulant. Atrial fibrillation (AF) is an irregular and often very rapid heart rhythm (arrhythmia) that can lead to blood …
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Smartwatches could help Fine-Tune brain implants for tremor patients
Knowledge-focused ENROLLING_BY_INVITATIONThe purpose of this research is to observe the daily loss of benefit from DBS therapy by performing a standardized set of tasks throughout the day while wearing an Apple Watch to collect movement and other physiological data.
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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New thai questionnaire could speed up carpal tunnel diagnosis
Diagnosis Recruiting nowThe Kamath and Stothard clinical questionnaire for diagnosing carpal tunnel syndrome (CTS) is a valid score for diagnosis of CTS. However it haven't been translated in to Thai version and the validity and accuracy of the Thai the Thai version have not been yet verified. The rese…
Sponsor: Siriraj Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:35 UTC
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Dementia study aims to cut unnecessary pills by listening to patients
Knowledge-focused CompletedThe purpose of this study is to compare patient priorities care (PPC) and usual care (UC) patients to identify differences in post-encounter medication changes, treatment burden (TBQ), and shared decision making in Older Patient Assessment of Chronic Illness Care (OPACIC), to und…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC