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116076 trials found · Page 4464 of 5804
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Blood marker may guide antibiotic use in High-Risk heart surgery
Knowledge-focused Recruiting nowAccording to the literature, presepsin was recommended not only as an effective indicator in the diagnosis of sepsis in intensive care units, but also as a reliable prognostic marker of postoperative inflammatory processes in cardiac surgery. Previous study carried out in Petrovs…
Phase: NA • Sponsor: Petrovsky National Research Centre of Surgery • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Simple tube trick may ease sore throat after surgery
Symptom relief CompletedPostoperative sore throat (POST) is a common morbidity following upper airway access-control with direct laryngoscopy-intubation (DLI) technique. Various reasons (size of the tracheal tube, cuff pressure, rough tube pass, and reattempts, among others) have been cited and manageme…
Phase: NA • Sponsor: Sir Ganga Ram Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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New study probes hidden language struggles in psychosis patients
Knowledge-focused Recruiting nowThis research concerns the study of language disorders of patients present in the spectrum of psychosis. It is indeed accepted that psychotic disorders are associated with language difficulties, which are only poorly highlighted thanks to reusable tools in clinical practice. Thes…
Phase: NA • Sponsor: Centre Psychothérapique de Nancy • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New combo approach for schizophrenia shows promise in small early study
Disease control TerminatedThe purpose of this study is to examine the role of clinical stability in functional recovery. in first episode schizophrenia.
Phase: PHASE4 • Sponsor: University of Miami • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Broccoli sprout supplement may shield gut from alcohol damage
Disease control CompletedChronic alcohol consumption leads to perturbations in gut microbiome balance (dysbiosis) and disruption of gut barrier integrity. As a result, bacteria, toxins, and metabolites can enter the blood stream and reach distant organs, triggering inflammation and oxidative stress. Thro…
Phase: NA • Sponsor: Louisiana State University Health Sciences Center in New Orleans • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Robot freezes eggs faster – but is it as good as humans?
Knowledge-focused Recruiting nowOocyte vitrification is an effective method of freezing which has been authorized in France since 2011. The arrival of this technique has led to real improvements in the survival rate of oocytes after warming compared to that observed after slow freezing, a method previously appl…
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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School stretching program eases Screen-Related back pain in teens
Symptom relief CompletedThis study evaluated whether a postural reeducation program could improve spinal posture and reduce musculoskeletal pain in adolescents who frequently use digital devices. Prolonged screen use is common among students and is often associated with inadequate sitting or standing po…
Phase: NA • Sponsor: University of Vigo • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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New toothpaste and mouthwash combo takes on plaque and gingivitis
Disease control CompletedQualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided. Subjects will return to the dental office for evaluation …
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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PSA after prostate surgery: a crystal ball for cancer?
Knowledge-focused Recruiting nowThis prospective observational study aims to evaluate the prognostic significance of early postoperative prostate-specific antigen (PSA) levels in patients undergoing radical prostatectomy for prostate cancer. No investigational interventions will be performed. All diagnostic pr…
Sponsor: Lithuanian University of Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Hormone link to fatty liver in young women under microscope
Knowledge-focused Recruiting nowThe researchers want to learn how androgens, a type of sex hormone, might affect nonalcoholic fatty liver (NAFLD) in young women over time. NAFLD happens when fat builds up in the liver which can cause damage to the liver such as inflammation or scarring. Young women with a cond…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Tiny Star-Shaped cuts may make gallbladder removal easier and less painful
Symptom relief CompletedLaparoscopic cholecystectomy is a common operation for gallbladder stones. In some patients, the removed gallbladder is difficult to extract through the umbilical port because it is large, thick-walled, or packed with stones. Surgeons commonly enlarge the fascial opening either v…
Phase: NA • Sponsor: Bangladesh Navy • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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20-Year review of lymphoma care reveals Real-World treatment success
Knowledge-focused Recruiting nowObservation of a cohort of 400 patients with different types of lymphomas.
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Pocket-sized 3D models could transform how students learn a key childbirth skill
Knowledge-focused CompletedThis randomized controlled trial aimed to evaluate the effectiveness of simulation-based education supported by a portable and mobile three-dimensional (3D) visual material on university students' knowledge of cervical dilation assessment, learning satisfaction, self-confidence i…
Phase: NA • Sponsor: Marmara University • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Cancer study aims to separate helpful treatments from hype
Knowledge-focused Recruiting nowThis pilot clinical trial aims to assess the real world quality of life and survival of patients treated with therapy that has preliminary evidence of efficacy but uncertainty of the magnitude of clinical benefit or cost effectiveness in subjects with cancer. The goal of this stu…
Phase: NA • Sponsor: British Columbia Cancer Agency • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Exercise program tested for rare heart condition
Symptom relief Recruiting nowExercise training in patients with heart failure and preserved ejection fraction (HFpEF) has been associated with an improvement in cardiorespiratory fitness and quality of life.
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jul 23, 2026 00:00 UTC
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Experimental combo for tough pancreatic cancer shows early promise
Disease control TerminatedTo learn if the study drug, YL-13027, is safe to give in combination with gemcitabine and nab-paclitaxel to participants with pancreatic cancer.
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Phone call checklists boost care for blood infection patients
Knowledge-focused CompletedThe main objective of this study is to investigate whether checklist-based close telephone consultation and process surveillance for S. aureus bacteraemia (SAB) can improve adherence to our in-house SAB-guidelines (prospective quality- improvement group). In addition, the effect…
Phase: NA • Sponsor: University Medicine Greifswald • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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800 patients to help build a crystal ball for gallstone surgery success
Knowledge-focused Recruiting nowThis prospective clinical cohort study will include patients with gallstones and abdominal pain scheduled for surgery (laparoscopic cholecystectomy). Data on quality of life, abdominal pain, gallstone disease, and patient characteristics will be collected before surgery. The outc…
Sponsor: Nordsjaellands Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Home visits for new moms: a simple idea that could reduce stress and boost confidence
Knowledge-focused OngoingThe purpose of this study is to assess the effectiveness of a new brief home visitation program delivered by non-nurse home visitors to 1) improve connections to community resources based on reported and assessed needs, 2) increase health self-efficacy, and 3) reduce maternal str…
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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One-Time therapy shows promise for child with One-Sided weakness
Symptom relief CompletedThis study describes a single pediatric case with hemiparesis who received a specialized physiotherapy intervention based on the Vojta method. The child, aged 15 years, was treated in a clinical setting by a physiotherapist certified in Vojta therapy during one intensive treatmen…
Phase: NA • Sponsor: Centro Integral Kaplan • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC