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127005 trials found · Page 4320 of 6351
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New study aims to stop coughing after sinus surgery
Symptom relief Not yet recruitingFunctional Endoscopic Sinus Surgery (FESS) is a widely performed procedure for the management of chronic rhinosinusitis and nasal polyposis. Despite being minimally invasive(1).Postoperative coughing, in particular, is a frequent complication that can increase venous pressure, di…
Phase 3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Chemo port study: right side vs left side breast cancer
Knowledge-focused Not yet recruitingChemotherapy is an essential component of breast cancer treatment. Frequent intravenous injections may lead to phlebitis and limited venous access, therefore implantable venous ports are increasingly used. The choice of port placement side in breast cancer patients is controversi…
Sponsor: Golestan University of Medical sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Vitamin d gel may fast-track braces: new trial
Knowledge-focused Not yet recruitingThis study will evaluate the effect of locally applied Calcitriol on dental and skeletal changes during upper canine retraction. It is a split-mouth randomized clinical trial, where Calcitriol will be locally applied on one side of the maxilla, and the other side will serve as co…
Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Eye drop combo aims to soothe redness in glaucoma treatment
Symptom relief Recruiting nowTo evaluate the effect of brimonidine tartrate 0.025% on conjunctival hyperemia in patients treated with netarsudil 0.02%/latanoprost 0.005% mono-therapy for intraocular pressure lowering.
Phase 4 • Sponsor: Insight Eyecare Specialties, Inc. dba Vision Source Eyecare, • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Which pump mode wins for exercise? new study tests SmartGuard vs temp target
Disease control Not yet recruitingPatients meeting the inclusion criteria will be identified. An informed consent form will be completed. Clinical data and baseline CGM will be collected at this appointment. During the session, an attempt will be made to establish a physical activity classification (PA0: inactive…
Sponsor: Hospital Universitario San Ignacio • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Experimental vaccine takes on tough pancreatic cancer
Disease control Not yet recruitingStudy design: This is a single-arm, open-label, dose-escalation and dose-expansion clinical study to evaluate the safety and efficacy of multiple doses of SapDM275 tumor vaccine injection in combination with the AG regimen for the treatment of patients with metastatic pancreatic…
Early phase 1 • Sponsor: The Third Xiangya Hospital of Central South University • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New study tests two promising therapies for stubborn back pain
Symptom relief Recruiting nowThe aim of this study is to investigate the effects of thoracolumbar fascia mobilization and ultrasound-guided thoracolumbar interfascial 5% dextrose injection on pain, range of motion, disability, quality of life, proprioception, and fascial thickness and echogenicity in patient…
Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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New consensus aims to soothe skin side effects of breast cancer treatment
Knowledge-focused By invitation onlySkin toxicity is one of the most common and impactful adverse effects of breast cancer treatment, affecting patients undergoing chemotherapy, targeted therapies, endocrine therapy, and radiotherapy. Current research and expert consensus highlight the importance of early, preventi…
Sponsor: Venus Research Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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MRI reveals hidden jaw disc tears in 282 patients
Knowledge-focused CompletedTo evaluate the presence of TMJ disc perforation on MRI and investigate its associations with internal disc derangements, disc configuration, condylar bone marrow signal patterns, joint effusion, and demographic or clinical variables such as age, sex, dental status, and pain seve…
Sponsor: Recep Tayyip Erdogan University Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New study tests which dental device moves molars best
Disease control OngoingComparative study between modified miniscrew-assisted rapid palatal expander and modified rapid palatal expander in molar distalization using CBCT.
Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New eye drop aims to ease dry eye symptoms and boost work productivity
Symptom relief Recruiting nowThis 1-month, 3-visit study will be conducted at the Southern College of Optometry (Memphis, TN), Kannarr Eye Care, LLC (Pittsburg, KS) and Complete Eye Care of Medina (Minneapolis, MN). Adults ≥18 years of age who have been diagnosed with DED for at least 6 months and who are cu…
Phase 4 • Sponsor: Southern College of Optometry • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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New study tests safer wrist access for heart patients with blocked arteries
Knowledge-focused Recruiting nowCoronary angiography and angioplasty are commonly performed through the radial artery at the wrist as this approach is associated with fewer bleeding complications and faster recovery. In some patients, the radial artery becomes occluded after prior procedures, requiring selectio…
Sponsor: National and Kapodistrian University of Athens • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Painkiller-blood thinner combo under scrutiny in cancer patients
Knowledge-focused Recruiting nowEvaluation of the Effect of metamizole (Optalgin®) on Anti-Xa Levels in Oncology Patients Receiving Direct Oral Anticoagulants (DOACs)
Sponsor: Rambam Health Care Campus • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can a pegboard test help track Parkinson's arm strength?
Knowledge-focused CompletedParkinson's patients who volunteer to participate in the study will be included. Parkinson's patients participating in the study will be referred from the SANKO University Hospital Neurology Outpatient Clinic. The assessments of patients referred from the Neurology Outpatient Cli…
Sponsor: Sanko University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New study probes arm muscle stiffness in duchenne patients
Knowledge-focused By invitation onlyMuscular dystrophies are hereditary and progressive skeletal muscle diseases that cause degeneration and loss of strength in the muscles. The most common form is Duchenne Muscular Dystrophy (DMD), which is X-linked recessive and develops due to a mutation in the dystrophin gene. …
Sponsor: Sanko University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Can a 5-Minute blood test save trauma patients from unnecessary treatment?
Knowledge-focused Recruiting nowBackground: Why This Study Matters When someone suffers a severe injury (like from a car crash), they can bleed heavily. One complication doctors often face is something called Trauma-Induced Coagulopathy (TIC). This is a condition where the blood doesn't clot properly, making bl…
Sponsor: Erasmus Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Can science predict who will get sick in a heatwave?
Knowledge-focused Recruiting nowThe escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans. Excess morbidity and mortality during heat waves provides strong evidence for fatal outcomes. However, it is unclear why some …
Sponsor: University of Thessaly • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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New study tests better ways to rebuild jawbone for dental implants
Disease control CompletedThis research is designed to evaluate and compare the clinical and radiographic outcomes of bovine bone graft (Medpark) versus extended sticky bone used for horizontal augmentation of atrophied esthetic area of maxillary ridge associated with simultaneous implant placement.
Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New imaging tricks could end guesswork for hand and foot skin conditions
Knowledge-focused OngoingPalmoplantar psoriasis and palmoplantar eczema are chronic inflammatory skin diseases that may show similar findings on the palms and soles, such as redness, scaling, thickening of the skin, fissures, itching, and burning. Because these conditions can look alike, distinguishing b…
Sponsor: Istanbul Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Can a green Tea-Infused frying oil tame blood fat spikes?
Knowledge-focused CompletedThe objectives of the study were to investigate effects of foods prepared in palm oil blended with canola oil containing surfactants and green tea extract on postprandial triglyceride levels in healthy volunteers. There were 22 subjects in the study. They were divided into 2 grou…
Sponsor: Chulalongkorn University • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC