Painkiller-blood thinner combo under scrutiny in cancer patients

NCT ID NCT07384013

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how metamizole (Optalgin), a common painkiller, changes the levels of blood thinners (apixaban or rivaroxaban) in cancer patients. Researchers will measure drug concentrations at several time points in 30 adults. The goal is to understand if metamizole interferes with these anticoagulants, which could affect bleeding or clotting risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

metamizole (Optalgin)

What this could lead to

If successful, this could help doctors safely combine metamizole with blood thinners in cancer patients, reducing bleeding or clotting risks.

What could go wrong

This is a small, early-stage observational study with only 30 participants, so results may not apply broadly. It does not test a new treatment, only measures drug interactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia blood coagulation disease cancer neoplasm vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rambam Health Care Campus

    RECRUITING

    Haifa, 31096, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••