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116076 trials found · Page 4309 of 5804
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Could a gentle leg wiggle protect your arteries while you sit?
Knowledge-focused Recruiting nowThe purpose of this study is to test the effects of leg exercise assistive paddling (LEAP) therapy during prolonged sitting (PS) on vascular and functional performance in those with peripheral artery disease (PAD) and age-matched controls. LEAP therapy is a novel application of p…
Phase: NA • Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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New training helps stroke survivors regain awareness after neglect
Symptom relief CompletedIt is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect). Individuals with neglect have difficulty paying attention to one side of their body or one side of the environment and therefore experience difficulty …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Brain-Controlled soundtrack boosts attention in small study
Knowledge-focused CompletedThis study aims to explore the potential of binaural beats, adjusted in real-time via EEG feedback, to positively influence brain states related to relaxation, focus, and cognitive performance. The investigators are examining how these auditory techniques can improve memory, atte…
Phase: NA • Sponsor: Texas Tech University Health Sciences Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:09 UTC
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New registry aims to unlock secrets of rare genetic hearing loss
Knowledge-focused Recruiting nowThis registry is designed to collect comprehensive information about the molecular genetic diagnoses and clinical information of individuals with CABP2-associated hearing impairment to support a natural history study.
Sponsor: University Medical Center Goettingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Veterans with PTSD take the wheel: racecar simulator may ease symptoms
Symptom relief CompletedNova Southeastern University and the Veterans trust through this line of research will strengthen community engagement and awareness for the need to recognize and provide treatment models for veterans diagnosed with PTSD. The goal is to improve self-regulatory mechanisms within t…
Phase: NA • Sponsor: Nova Southeastern University • Aim: Symptom relief
Last updated Jun 26, 2026 12:39 UTC
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New pill CT7439 enters human testing for Hard-to-Treat cancers
Disease control Recruiting nowThis modular, multi-part, multi-arm, Phase 1/2, FIH study allows the evaluation of the safety and tolerability of CT7439, dosed as a monotherapy and in combination with anticancer treatment in participants with solid malignancies.
Phase: PHASE1, PHASE2 • Sponsor: Carrick Therapeutics Limited • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New antibiotic paste could replace drilling for Kids' cavities
Disease control CompletedThis study aims to compare the effectiveness of Lesion Sterilization and Tissue Repair (LSTR) with conventional pulpectomy in treating pulpal lesions in primary molars of pediatric patients aged 4 to 10 years. LSTR is a minimally invasive method that uses antibiotic paste to disi…
Phase: NA • Sponsor: taymour abuawwad • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Appalachia study tests tobacco rules in simulated store
Knowledge-focused ENROLLING_BY_INVITATIONThe goal of this project is to look at the effect of proposed tobacco product regulations in Appalachian Kentucky. Appalachian Kentucky is a diverse and underserved rural area that would benefit from more tobacco regulation research. Researchers will study the effects of three pr…
Phase: NA • Sponsor: Mikhail N Koffarnus • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New obesity drug passes early safety check
Symptom relief CompletedThe main purpose of this study is to evaluate the safety and tolerability of the study drug known as LY3532226 in participants with obesity. Blood tests will be performed to check how much LY3532226 gets into the bloodstream and how long it takes the body to eliminate it followin…
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Group therapy shows promise for easing postpartum depression and anxiety
Symptom relief CompletedExperiencing postpartum mood and/or anxiety disorders (like postpartum depression; PMADs) can make parenting challenging, but group therapy may help both these parents and their babies. This study will test whether postpartum parents with PMADs find a 12-session parenting group t…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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New pill may ease leg pain from narrowed spine
Symptom relief CompletedThis study is to evaluate the Effectiveness and Safety of Dong-A Opalmon® Tablet in Patients With Acquired Lumbar Spinal Stenosis
Sponsor: Dong-A ST Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Do clear aligners protect tooth bone better than braces? a head-to-head trial
Knowledge-focused CompletedThis study compares two common ways of straightening teeth in adults who have mild-to-moderate crowding of the lower front teeth and do not need any teeth removed: clear aligners and traditional fixed braces. The main aim is to find out whether the two methods differ in how they…
Phase: NA • Sponsor: Future University in Egypt • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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New shot for high cholesterol passes first safety test in humans
Disease control CompletedIt is a randomized, double-blind, single-dose, placebo-controlled phase I clinical trial. The study plans to conduct four to six dose groups of dose 1, dose 2, dose 3, dose4, dose5 (optional), and dose 6(optional). Eight subjects will be enrolled for each dose group, with six adm…
Phase: PHASE1 • Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 17:18 UTC
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Can learning about pain change how your body reacts to it?
Knowledge-focused CompletedIn this study, the investigators are comparing two types of education for older adults with knee osteoarthritis: standard biomedical education focusing on the disease process, and a newer approach called pain neuroscience education (PNE), which teaches about the complexity of pai…
Phase: NA • Sponsor: Lisa Carlesso • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Blood pressure pills may change brain blood flow in seniors
Knowledge-focused CompletedHigh blood pressure (BP) is a public health problem worldwide. Nearly three-quarters of older adults (age \~60 years) in the United States have high BP. High BP links to many health problems, like stroke. Drug treatments are typically used in clinics to reduce high BP and the ris…
Phase: EARLY_PHASE1 • Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Simple home workouts may ease mental distress for kidney dialysis patients
Symptom relief CompletedThe aim to investigate the level of psychological distress on patients undergoing hemodialysis at Al-Suwaiq Renal dialysis center as well as to explore the effectiveness of home-based exercise method in reducing such psychological distress, depression, and anxiety. the main ques…
Phase: NA • Sponsor: Oman Ministry of Health • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Eye exercises after surgery may help keep eyes aligned
Disease control CompletedThe aim of this study is to determine the patient status through its follow up period and weather the eye alignment and eye control are as the same as the last physiotherapy treatment session or there is any deterioration of them.
Sponsor: Amany Refaat Mohamed Abdel Wahid • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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App boosts balance exercise adherence in dizzy patients
Symptom relief CompletedA randomized controlled trial to assess the efficacy of an app-assisted vestibular rehabilitation in increasing adherence to VR and treatment outcomes
Phase: NA • Sponsor: University of Haifa • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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New breathing device for newborns proves just as effective as current standard
Disease control CompletedThe aim of the study is to compare the non-inferiority of the Mix-safe T-piece resuscitator (intervention group) to the Neopuff T-piece resuscitator (control group) in providing respiratory assistance during the resuscitation of newborns. If Mix-safe is proven to be non-inferior,…
Phase: NA • Sponsor: Dr Cipto Mangunkusumo General Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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AI magic: can doctors spot fake colonoscopy images?
Knowledge-focused CompletedThe study addresses the limitations of current AI systems in gastrointestinal endoscopy, which are tipically trained with data from a single type of endoscopy processor and have limited expert-annotated images. The investigators aim to develop and validate EndoStyle, an AI system…
Sponsor: Wuerzburg University Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:34 UTC