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116076 trials found · Page 4259 of 5804
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New nanoparticle therapy tested for autoimmune liver disease – first human trial complete
Disease control CompletedThe goal of this clinical trial is to learn what happens to PVT201 when it enters your body and how it affects your immune system. It will also learn about the safety of PVT201 after a single dose. The main questions it aims to answer are: Will participants experience any side e…
Phase: PHASE1 • Sponsor: Parvus Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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New study reveals risks of breathing tube placement in obese surgery patients
Knowledge-focused CompletedBackground: Difficult airway in bariatric patients presents significant challenges during anesthesia, impacting patient safety and surgical outcomes. This study aims to estimate the incidence of difficult airway in bariatric patients undergoing surgery. Materials and Methods: Th…
Sponsor: : Manuel Alberto Guerrero Gutierrez • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can a Nurse-Led program help psoriasis patients take control?
Knowledge-focused CompletedBackground Psoriasis is a chronic inflammatory skin disease causing reduced quality of life. Psoriasis patients are often insufficiently informed about their disease with its treatment possibilities leading to non-adherence of treatment resulting in unsatisfactory patient outcome…
Phase: NA • Sponsor: School of Health Sciences Geneva • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Can a breathing technique ease asthma fatigue?
Symptom relief CompletedThis study was designed as a pre-test-post-test randomized controlled experimental trial to determine the effects of buteyko breathing technique application on fatigue, exercise capacity, and asthma control in asthma patients.The study, planned as a randomized controlled experime…
Phase: NA • Sponsor: University of Gaziantep • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Scientists unlock secrets of flu Vaccine's age gap
Knowledge-focused CompletedThe goals of this study are to better understand the human immune response to influenza vaccines, specifically the live attenuated (weakened) influenza vaccine given as a nasal spray. Better understanding why this vaccine does not work as well in adults as it does in children may…
Phase: PHASE4 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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VR training could change how future nurses treat dementia patients
Knowledge-focused CompletedThis quasi-experimental study focuses on Indonesian nursing students and aims to examine the effectiveness of virtual reality (VR) dementia educational programs. The study addresses the following research questions: 1. What is the current state of knowledge and awareness about d…
Phase: NA • Sponsor: Universitas Airlangga • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Ear seeds may ease C-Section pain without drugs
Symptom relief CompletedIntroduction: Severe acute pain after cesarean section is an independent risk factor for the development of chronic pain and increases the risk of postpartum depression threefold. Pain also reduces the mother's ability to breastfeed and care for her child. This study aimed to ev…
Phase: NA • Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Grief check: nurses test brief support for the bereaved
Knowledge-focused CompletedGrief is the response to the death of a loved one. The loss of a loved one requires a grieving process that allows one to adapt to the new situation. The main objective of this study is to identify people in a situation of bereavement who attend nursing consultations in Primary C…
Phase: NA • Sponsor: Servicio Canario de Salud • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Cold therapy offers simple pain relief for arthritis patients
Symptom relief CompletedThe aim of this thesis is to examine the effects of cold application on pain, disease activity, and quality of life in patients with Rheumatoid Arthritis. Currently, non-pharmacological interventions, such as cold therapy, are utilized less frequently than pharmacological treatm…
Phase: NA • Sponsor: Saglik Bilimleri Universitesi • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Massage gun study reveals best intensity for football performance
Knowledge-focused CompletedThis randomized crossover study investigates the acute effects of different percussive massage intensities on agility, jumping, strength, and power performance in trained male football players. Participants complete three experimental conditions (no massage, low-intensity percuss…
Phase: NA • Sponsor: Monira Aldhahi • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can a smartphone app keep cancer patients safer during treatment?
Knowledge-focused Recruiting nowThis study is being done to better understand patient experiences with using a mobile application, known as Vigilant, to monitor symptoms as outpatients and to gather preliminary data on the potential clinical benefit to remote monitoring of adverse events.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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New lens aims to sharpen sight at all distances
Symptom relief Recruiting nowThe study purpose is to demonstrate safety and performance of bilateral implantation of LuxBoost intraocular lenses compared with the LuxGood Monofocal lens.
Phase: NA • Sponsor: Cutting Edge SAS • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Hello bundle: a simple greeting to fight ICU burnout?
Knowledge-focused CompletedBurnout among healthcare professionals in intensive care units (ICUs) is a prevalent concern with significant implications for both staff well-being and patient care outcomes. This protocol outlines a cluster randomized controlled trial designed to evaluate the effectiveness of t…
Phase: NA • Sponsor: Saint-Louis Hospital, Paris, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Can a simple ankle brace help stroke survivors walk and think at the same time?
Knowledge-focused CompletedThe goal of this clinical trial is to learn the effect of carbon fiber ankle foot rothosis (AFO) on dual-task walking perfromance and cognitive load for stroke patients. The main questions it aims to answer are: Does wearing carbon fiber AFO can improve gait and secondary task …
Phase: NA • Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Mind over menu: can meditation make your diet greener?
Knowledge-focused CompletedThe goal of this randomized controlled clinical trial is to determine whether a mindfulness-based intervention, in addition to nutritional education, improves healthy and sustainable eating habits in 53 young adults aged 18 to 35 years with low adherence to a sustainable diet.
Phase: NA • Sponsor: University of Turin, Italy • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Scientists dive into amniotic fluid to unlock preterm gut mysteries
Knowledge-focused Recruiting nowBackground: Necrotizing enterocolitis (NEC) and sepsis in preterm infants have been linked to intestinal immaturity and preclinical gut microbiota alterations. An important yet understudied contributor in the development of the gastrointestinal tract (GIT) is amniotic fluid (AF)…
Sponsor: Maxima Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:16 UTC
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Video games may improve scoliosis treatment in teens
Disease control CompletedThe aim of this study was to investigate the effect of technology-based exercises on treatment success in adolescents with idiopathic scoliosis. Within the scope of the study, thirty patients with AIS will be randomly allocated to two groups. The control group will apply a progr…
Phase: NA • Sponsor: hande tunc • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Could a cream made from breast milk prevent NICU stays for low blood sugar babies?
Symptom relief Recruiting nowProlact CR (cream) is a fat supplement that is derived from pasteurized human donor milk. It has been utilized in babies who are born premature in the neonatal intensive care unit (NICU) setting to improve growth while avoiding cow milk exposure. There is no literature on the use…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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AR goggles could help surgeons see kidney stones better
Knowledge-focused CompletedThis project aims to develop an augmented reality (AR) tool to enhance skill acquisition for endoscopic kidney stone surgery. Of the 100,000 patients who undergo an endoscopic kidney stone treatment annually in the United States, 25% will require a repeat stone surgery within 20 …
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Can phone Check-Ins ease cancer treatment side effects?
Symptom relief Recruiting nowIn this clinical trial, symptom monitoring (interactive voice response \[IVR\] is compared to automated telephone symptom management \[ATSM\] and telephone interpersonal counseling \[TIPC\]) for reducing symptom burden and psychological distress (depressive and anxiety symptoms) …
Phase: NA • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC