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127005 trials found · Page 4181 of 6351
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Micro-Dose sedative calms Post-Surgery agitation
Symptom relief OngoingThis prospective randomized controlled study will be conducted to evaluate the effect of preoperative single, micro-dose of dexmedetomidine (0.3μg/kg) on the incidence and severity of EA in adults undergoing Septoplasty surgeries
Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Could a blood clot replace gum surgery for dental implants?
Disease control Recruiting nowAn effective biological seal is crucial for protecting and supporting dental implants, particularly in the anterior region for the desired esthetic outcome.PRF membrane and CTG has been utilized to improve peri-implant soft tissue thickness and increase the width of keratinized t…
Sponsor: Gulf Medical University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a gentler solution replace acid for brighter teeth?
Symptom relief Recruiting nowThis clinical trial will be conducted to assess the clinical efficacy of using Antivet cleaning enamel solution or hydrochloric acid and phosphoric acid in microabrasion technique for mild to moderate intrinsic stained teeth.
Phase 1 • Sponsor: Misr University for Science and Technology • Aim: Symptom relief
Last updated Jul 18, 2026 00:00 UTC
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Blood test may predict delirium risk in elderly hip surgery patients
Knowledge-focused Recruiting nowNaples Prognostic Score (NPS) originally developed to predict outcomes in inflammatory and malignant conditions; we asked if it can effectively predict postoperative delirium (POD) in elderly patients undergoing hip surgery? NPS integrate markers such as albumin, neutrophil-to-ly…
Sponsor: South Valley University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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New app aims to help cancer patients spot medication dangers at home
Knowledge-focused Recruiting nowThis clinical trial evaluates the usefulness of a self-monitoring platform for tracking medication safety events and concerns in patients with lung, colorectal, breast, and prostate cancer. Patients receiving oral anticancer agents often encounter challenges in managing complex t…
Sponsor: University of Michigan Rogel Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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HPV education trial aims to boost screening and vaccination among young women
Knowledge-focused CompletedType of Study: This study was planned to be an observational study. Purpose of the Study: To evaluate the impact of HPV education given to women on their knowledge levels and HPV screening and vaccination.The main question\[s\] it aims to answer \[is/are\]: H1: There is a diffe…
Sponsor: Ufuk University • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Can a heart monitor predict blood pressure drops during dialysis?
Knowledge-focused Recruiting nowThe Analgesia Nociception Index (ANI) reflects the balance between sympathetic and parasympathetic tone. It is based on a specific interpretation of the R-R interval variation. During fluid removal by net ultrafiltration in patients with fluid overload and continuous renal replac…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Global study tracks Real-World impact of new heart drug
Knowledge-focused Recruiting nowThe purpose of this study is to: * Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-CM) treated with vutrisiran in routine clinical care * Describe treatment patterns of adult patients with ATTR-CM treated …
Sponsor: Alnylam Pharmaceuticals • Aim: Knowledge-focused
Last updated Sep 10, 2026 04:00 UTC
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New study aims to boost safety of targeted radiation cancer treatment
Knowledge-focused Recruiting nowTargeted Radionuclide Therapy (TRT) is a treatment modality used in nuclear medicine to target cancer cells while preserving surrounding healthy tissues. This approach is based on the use of radiopharmaceuticals (RPs)-compounds that combine a radioactive isotope with a molecule d…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Heart plaque 'Fingerprinting' could guide better angioplasty
Knowledge-focused Not yet recruitingTo investigate whether pre-procedural OCT-derived de novo coronary lesion phenotype (lipid-rich, fibrotic, calcific; and ACS mechanisms such as plaque rupture/erosion/calcified nodule) is associated with clinical outcomes after DCB angioplasty.
Sponsor: Fondazione Ricerca e Innovazione Cardiovascolare ETS • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New study tracks pain and walking recovery after amputation
Knowledge-focused Recruiting nowThe primary aim of this study is to characterize the trajectory of pain and functional recovery in the first post-operative period following a limb amputation. Secondarily, this study aims to conduct an exploratory analysis to evaluate potential associations between clinical, dem…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Home device aims to boost brain power after injury
Symptom relief CompletedThe purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous vagus nerve stimulation (tVNS) at home, to enhance cognitive recovery in patients with mild-moderate traumatic brain injury (TBI).
Sponsor: Shirley Ryan AbilityLab • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Study probes hidden effects of Pre-Surgery cancer therapy on tissue and recovery
Knowledge-focused Recruiting nowThis prospective study investigates the effects of neoadjuvant therapy on endothelial function, microvascular tissue density, and tissue fibrosis in patients with colorectal cancer and their association with perioperative complications. The primary objective is to assess differen…
Sponsor: Osijek University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Needles vs. botox: which eases grinding pain best?
Symptom relief Completed1. Aim: The aim of this study is to prospectively compare the clinical efficacy of Dry Needling (DN), Nabota (PrabotulinumtoxinA), and Dysport (AbobotulinumtoxinA) treatments on the thickness of masseter and anterior temporal muscles and pain intensity (VAS) in patients diagnosed…
Sponsor: Recep Tayyip Erdogan University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Scientists scan young brains to map how connections are pruned
Knowledge-focused By invitation onlyThe study will use a PET-based measure of brain cell (neuron) connections (synapses) in young adults who have also obtained an MRI, to assess how the loss of brain cell connections (synaptic pruning) is captured by MRI-based measures. This will inform youth MRI studies to underst…
Sponsor: Beatriz Luna • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Ultrasound vs. Old-School exam: which wins for dialysis patients?
Knowledge-focused OngoingFluid overload (when the body has too much fluid), is one of the reasons why people on home dialysis need to go to the hospital. Fluid overload commonly presents as trouble breathing and leg swelling. Traditionally, doctors check for this by asking patients if they have any sympt…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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New study aims to decode a hidden threat to Children's health
Knowledge-focused Recruiting nowThis study aims to characterize the pediatric cryptosporidiosis disease profile with respect to clinical presentation.
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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What makes insulin stop working? scientists investigate healthy people
Knowledge-focused Recruiting nowThe goal of this intervention study is to learn more about what causes insulin resistance in otherwise healthy adults, and how short-term changes in physical activity or diet may influence it. The study includes healthy male and female participants aged 25 to 55 years, who meet s…
Sponsor: University of Copenhagen • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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Music tweaked by tech may raise 'Love Hormone' levels
Knowledge-focused Recruiting nowThe investigator aim to investigate wheather music modified by sonic augmentation technology can produce increasing oxytocin levels with minimal to no side effects in a highly standardized setting
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Freezing lung biopsies: a safer way to diagnose?
Knowledge-focused Recruiting nowTransbronchial cryobiopsy is a relatively recent technique, increasingly used for the diagnosis of various respiratory diseases, including neoplasms, diffuse interstitial lung diseases (ILDs), and rejection after lung transplantation. Currently, its use is included in European re…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC