What makes insulin stop working? scientists investigate healthy people

NCT ID NCT07255807

First seen Dec 29, 2025 · Last updated Jun 19, 2026 · Updated 30 times

Summary

This study looks at why some healthy adults develop insulin resistance, a condition where the body doesn't use insulin well. Researchers will ask 80 participants to either reduce physical activity for 14 days or eat a high-fat diet for 3 days. They will then measure changes in insulin sensitivity and look at blood and tissue samples to find molecular clues. The goal is to better understand how lifestyle and biology interact, not to test a treatment.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • August Krogh Building

    Copenhagen, 2100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Insulin Resistance Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.