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Could a gentler solution replace acid for brighter teeth?

NCT ID NCT07709286

Symptom relief Sponsor: Misr University for Science and Technology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This trial compares a new cleaning solution called Antivet against two acids (phosphoric and hydrochloric) for removing mild to moderate stains from teeth using a microabrasion technique. Participants are people aged 16 to 50 with stained front teeth. The goal is to see if Antivet works as well as or better than the standard acid treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Antivet cleaning enamel solution
What this could lead to
If effective, Antivet could offer a gentler alternative to acid-based treatments for removing tooth stains.
What could go wrong
This is a small, early-phase trial, so results may not apply broadly, and Antivet may not outperform standard acids.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

1. Eligibility Criteria of participants: Inclusion Criteria: * Patients with moderate to mild stained teeth. * 16-50 years. * Males or Females. * Co-operative patients approving to participate in the study. Exclusion Criteria: * High caries index with poor oral hygiene. * Severe medical complications. * Pregnancy. * Xerostomia. * Lack of compliance. * Smokers 2. Eligibility Criteria of teeth: Inclusion Criteria of teeth: * Anterior teeth. * Mild to moderate intrinsic or extrinsic stains. * Vital and non-sensitive anterior teeth. Exclusion criteria of the teeth: * pitted enamel. * carious teeth. * Deep lesions. * Severe periodontal problems. * Previous treatment for the stained teeth

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Conditions

The condition(s) this trial relates to.

dental fluorosis Tooth Discoloration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Teeth staining

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Egyptian Russian University

    RECRUITING

    Badr, Cairo Governorate, 11829, Egypt

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