A brighter smile without fluoride? new trial tests whitening toothpaste against stains

NCT ID NCT07761715

Completed Symptom relief Sponsor: Boka LLC Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study compares a non-fluoride whitening toothpaste to a standard fluoride toothpaste to see which better removes surface stains from teeth. About 100 adults will brush with one of the two toothpastes at home for four weeks. Researchers will measure tooth color changes using a standard stain index to determine if the whitening toothpaste improves whiteness more than the control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: A non-fluoride whitening toothpaste with stain-removing properties
What this could lead to: If effective, this toothpaste could offer a simple, at-home way to brighten teeth and reduce surface stains without fluoride.
What could go wrong: The trial is small and short-term, and results may not reflect long-term whitening or work for everyone. Tooth sensitivity or gum irritation are possible with whitening products.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Tooth Discoloration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TEETH STAINING

Contacts and locations

Locations

Salus Research, Inc.

Fort Wayne, Indiana, 46825, United States

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Other studies related to the condition(s) this trial covers.