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Successful endodontic treatment and a predictable outcome can only be achieved by effective root canal debridement, irrigation, and elimination of microorganisms . The outcome of endodontic treatment performed in controlled clinical environment has demonstrated success rate arou…

The goal of this clinical trial is to assess the effect of four different types of mouthwash on socket healing after surgical extractions in male or female patients aged 18 years and older who have a unilateral impacted mandibular third molar indicated for extraction. The main qu…

Psoriasis is a common immune-mediated inflammatory skin disease affecting at least 100 million individuals worldwide. In Egypt, the prevalence of psoriasis ranges between 0.19% and 3% of the Egyptian people. It is associated with poor quality of life, reduced life expectancy and…

This study implemented a personalized 6-month diet and exercise program to promote weight loss. Participants were recruited from outpatient clinics at the Department of Family Medicine, National Taiwan University Hospital. Overweight and obese adults were eligible, defined as fol…

Axillary web syndrome (AWS) is a complication associated with breast cancer surgery, characterized by pain, functional limitation of the shoulder and decreased quality of life. There are several physical treatment options to reduce pain and improve the functionality of the upper …

Fibular neuropathy frequently manifests as foot drop, muscle weakness, altered gait, and sensory loss, all of which severely reduce mobility and quality of life. There is still uncertainty regarding the efficacy of kinesio taping (KT), proprioceptive neuromuscular facilitation (P…

This prospective observational study aims to determine the factors affecting the success of unilateral spinal anesthesia in patients undergoing orthopedic lower extremity surgery. Unilateral spinal anesthesia is preferred to minimize unwanted effects such as hypotension and to pr…

Craniotomy presents true anesthetic challenges, mainly due to the need to optimize cerebral perfusion, facilitate brain relaxation, achieve rapid emergence for neurologic assessment, and minimize perioperative complications.

Pilates exercises have been shown to be effective for a range of outcomes; however, it is unclear whether they can effectively contribute to fat mass reduction, especially when compared with a technique known to be effective for this purpose, such as aerobic training. Furthermore…

The goal of this clinical trial is to compare three-point and six-point Genicular Nerve Radiofrequency Ablation (GNRFA) in adults with chronic knee osteoarthritis (KOA). The main question it aims to answer is whether six- target GNRFA technique is more efficacious than standard t…

The goal of this trial is to evaluate whether a family participation training intervention can reduce caregiver strain and health worker workload, and improve patient outcomes and collaboration in the medicine wards of Chittagong Medical College Hospital (CMCH). General objectiv…

This is a Phase 1, randomized, blinded, placebo controlled, single ascending dose (SAD) study of BBT001 in healthy volunteers (HVs) and adult patients with moderate to severe Atopic Dermatitis (AD).

The aim of this study was to evaluate the relationship between treatment outcomes and central sensitization levels in patients who received intra-articular injections for frozen shoulder.

The Aim of this study is to test the effectiveness of locally applied resveratrol as an adjunct to scaling and root planing in the treatment of periodontitis (primary outcome) . Also to assess the level of COX-2 and superoxide dismutase (SOD) in the gingival crevicular fluid samp…

PREM-IMPACT is a UK-based observational study exploring how caring for a very premature baby-particularly one affected by necrotising enterocolitis (NEC)-impacts families over the first year after hospital discharge. NEC is a serious bowel disease that can occur in premature babi…

Starts and turns play an important role in swimming performance, with starts accounting for around a quarter of the total time achieved in a 50m freestyle race and have been recommended as a high priority area for improvement by York City Baths Club (YCBC). The relationship betwe…

This study was designed to develop and evaluate the effectiveness of a web-based supportive care program for individuals diagnosed with colorectal cancer undergoing cancer treatment. The program's effectiveness is evaluated based on the symptom burden and quality of life experien…

The main objective of this observational trial is to explore the validity and reliability of DANU smart socks when used for mobility assessments in people with Parkinson's. Using a series of laboratory gold standard equipment, this project aims to compare the metrics observed by …

The e-SINCERE study will evaluate whether providing stable cell phones and digital navigation assistance helps patients overcome ICT barriers and connect more successfully with community services. The study will begin with patients in the UHealth ED, with additional sites added i…

This cluster randomized controlled trial aims to evaluate the effectiveness of an educational board game compared to a lecture-based intervention on improving knowledge, attitudes, and confidence in dengue-related practice among nurses working in primary healthcare (PHC) units. A…