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127005 trials found · Page 3545 of 6351
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Family lessons may ease stress and boost scoliosis treatment in teens
Symptom relief CompletedYağmur KİRMİK, Investigation of the Effect of Family Education on Stress, Deformity Perception, Quality of Life, and Treatment Adherence in Individuals with Adolescent Idiopathic Scoliosis, Hasan Kalyoncu University, Graduate Education Institute, Department of Physiotherapy and R…
Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated Jul 22, 2026 00:00 UTC
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Heart health under the microscope: landmark study on Gender-Affirming hormones
Knowledge-focused By invitation onlyGender-affirming hormone therapy is today a well-established treatment for individuals experiencing gender-incongruence. However, little is known about the long-term effects of gender-affirming hormone therapy on the cardiovascular system and it is unknown whether gender-affirmin…
Sponsor: University Hospital, Akershus • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Can a special light boost brain health in glaucoma patients?
Knowledge-focused Recruiting nowThe goal of this study is to understand how light sensitivity in the eye affects sleep, mood, alertness, and cognition in adults with glaucoma compared to healthy individuals aged 45-75 years. The main questions it aims to answer are: 1. Do patients with glaucoma experience poo…
Sponsor: National University of Singapore • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Can a simple questionnaire capture the true toll of metabolic surgery?
Knowledge-focused By invitation onlyPURPOSE OF THE STUDY?This study aims to assess patients' quality of recovery and satisfaction after metabolic surgery at a tertiary hospital in South Africa using two validated questionnaires. These assess postoperative comfort, return to normal activities, symptoms such as pain,…
Sponsor: Sefako Makgatho Health Sciences University • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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Donate your mammogram to train AI for better breast cancer detection
Knowledge-focused Recruiting nowThis study aims to develop AI models to better read diagnostic mammograms for various populations and types of breast cancer, using the images that participants donate and their responses from study questionnaire to improve patient outcomes. This study also aims to provide mammog…
Sponsor: University of Central Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Eyes may reveal hidden clues about endometriosis
Knowledge-focused Recruiting nowThere is increasing evidence that examining our eyes can tell us a lot of information about our health, and systemic diseases. Our plan is to compare the images taken of the back of eyes of women who have endometriosis with those of women who don't. We want to study what eyes can…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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New injectable schizophrenia drug enters early human testing
Disease control Recruiting nowA study to evaluate the safety, tolerability, and PK of an injectable form of KarXT in participants with schizophrenia
Phase 1 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Exercise showdown: HIIT vs. combined training for postmenopausal health
Knowledge-focused CompletedIntroduction: Menopause is associated with body composition change, an increase in the cardio-metabolic risk factor for oxidative stress. Nevertheless, it has been suggested that regular physical training is an effective non-pharmacological intervention to reduce oxidative stress…
Sponsor: University of Valladolid • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New blood test may predict bleeding danger for cancer patients on clot drugs
Knowledge-focused Recruiting nowPulmonary embolism, the second leading cause of death in cancer patients, is effectively treated with anticoagulants. In patients with cancer-associated thrombosis (CAT), the use of anticoagulants is associated with 10 to 15% of bleeding in the first 6 months. Most of the guideli…
Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Nurse-Led teams may cut hospital returns for patients with multiple illnesses
Disease control OngoingThe goal of this clinical trial is to evaluate whether a nurse practitioner-led multidisciplinary team (NP-led MDT) intervention can improve the use of guideline-directed medical therapy (GDMT) and short-term clinical outcomes in hospitalized adults with multimorbidity in a multi…
Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Online mindfulness program aims to ease chemo stress in breast cancer patients
Symptom relief CompletedThe goal of this prospective, waitlist-controlled, 1:1 randomized study is to evaluate if an online mindfulness-based intervention (MBI) reduces treatment-related stress levels among patients with breast cancer receiving chemotherapy. The main questions it aims to answer are: *…
Sponsor: Medicos e Investigadores en la Lucha contra el Cancer de Mama • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Light-Based eye test could spot glaucoma risk early
Knowledge-focused Recruiting nowThis pilot study evaluates the biomechanical properties of the cornea in glaucoma patients using Brillouin microscopy, a non-contact imaging technique. The study aims to compare corneal stiffness between patients with normal-tension glaucoma, high-tension glaucoma, and healthy co…
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC
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Can a new teaching mix boost Doctors' confidence in endocrine crises?
Knowledge-focused CompletedThis randomized controlled trial evaluates whether an integrated online-offline multimodal teaching approach combining Problem-Based Learning (PBL), Case-Based Learning (CBL), and Case Three-Dimensional Teaching Method (CTTM) improves clinical self-efficacy and hands-on proficien…
Sponsor: Chaohu Hospital of Anhui Medical University • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Can a tropical fruit rind help Pre-Diabetic obesity? new study investigates
Disease control CompletedGarcinia cambogia, rich in hydroxycitric acid (HCA), has been suggested to promote weight loss and improve metabolic parameters. Evidence regarding its efficacy in pre-diabetic obese adults remains limited. Objective: To evaluate the effects of Garcinia cambogia rind powder supp…
Sponsor: University of Lahore • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New blood test may spot deadly pneumonia in ventilator patients earlier
Diagnosis Not yet recruitingmechanically ventilated for 48 hours or more and subsequently develop ventilator-associated pneumonia (VAP). After obtaining approval from the local ethical committee at the Faculty of Medicine, El-Minia University, and informed consent from first-degree relatives, patients will …
Sponsor: Esraa Hamdy Thabit Riad • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC
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Which magnesium strategy saves lives in the ICU?
Knowledge-focused CompletedThis study looks at how different ways of giving magnesium (a nutrient) affect the risk of death within 28 days for adults with low magnesium levels who are in the intensive care unit (ICU) for non-heart-related reasons. We will use data from past ICU patients (2008-2019) to comp…
Sponsor: Fujian Provincial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Chest muscle check could cut breathing tube failures
Knowledge-focused Recruiting nowIncreased days of MV are not without hazards, including barotraumas and ventilator-associated pneumonia. Similarly, premature separation of MV is associated with increased mortality secondary to adverse cardiorespiratory events. Therefore, the time of weaning should be wisely eva…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:46 UTC
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New app aims to boost quality of life for head and neck cancer survivors
Symptom relief OngoingThis study evaluates the development, implementation and effectiveness of a nurse-led eHealth support tool designed to improve quality of life and survivorship outcomes among adults treated for head and neck cancer. The intervention integrates symptom monitoring, self-management …
Sponsor: Royal College of Surgeons, Ireland • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New MS diagnostic criteria put to the test in Real-World study
Diagnosis Recruiting nowThe new diagnostic criteria for multiple sclerosis (MS) were published in October 2025 (Montalban et al. 2025). They introduce significant changes compared to the previous criteria from 2017: inclusion of previously "borderline" forms and use of new imaging techniques, inclusion …
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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Wearable sensors could spot patient decline earlier than standard checks
Knowledge-focused Recruiting nowUnsafe patient care remains a major contributor to global morbidity and mortality. In surgical wards, postoperative patients are typically monitored intermittently using the National Early Warning Score (NEWS-2), leaving periods during which clinical deterioration may go undetect…
Sponsor: University Hospital, Akershus • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC