New injectable schizophrenia drug enters early human testing

NCT ID NCT07061288

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-stage study is testing a long-acting injectable form of the drug KarXT in 116 people with schizophrenia. The main goal is to check the drug's safety and how the body processes it. Researchers hope this injectable version could offer a more convenient treatment option that lasts longer between doses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: KarXT (also known as BMS-986510)
What this could lead to: If successful, this could lead to a longer-lasting injectable treatment option for schizophrenia, potentially improving medication adherence and symptom control.
What could go wrong: This is an early Phase 1 study focused on safety and dosing, not yet on effectiveness. The injectable form may cause side effects or not work as well as the oral version. Results are preliminary and may not lead to a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SCHIZOPHRENIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA

Contacts and locations

Locations

Atlanta Center for Medical Research
RECRUITING

Atlanta, Georgia, 30331, United States
CenExel iResearch, LLC
RECRUITING

Decatur, Georgia, 30030, United States
Collaborative Neuroscience Research, LLC
RECRUITING

Los Alamitos, California, 90720-3118, United States
Community Clinical Research
RECRUITING

Austin, Texas, 78754, United States
Hassman Research Institute Marlton Site
RECRUITING

Marlton, New Jersey, 08053, United States
Innovative Clinical Research, Inc.
RECRUITING

Miami Lakes, Florida, 33016, United States
Research Centers of America ( Hollywood )
RECRUITING

Hollywood, Florida, 33024, United States
Uptown Research Institute
RECRUITING

Chicago, Illinois, 60640, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.