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127005 trials found · Page 2886 of 6351
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Eat in 10 hours, live better? new trial tests Time-Restricted eating for metabolic syndrome
Disease control Recruiting nowIn a randomized controlled trial, the investigators intend to measure the health impact of time restricted eating (TRE) in patients with metabolic syndrome (with elevated blood pressure and at least 2 of the following: increased waist circumference, abnormal cholesterol levels, e…
Phase 2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New heart device tested in 500 chinese patients: will it tame irregular heartbeats?
Disease control Recruiting nowTo obtain real world data on the use of, and provide continued evidence on safety and effectiveness of the FARAPULSE™ Pulsed Field Ablation (PFA) system when used per hospitals' standard of care in Chinese population.
Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New drug hopes to regrow hair in severe alopecia
Disease control Recruiting nowThis is a randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of FB102 in patients with severe to very severe alopecia areata (AA).
Phase 1 • Sponsor: Forte Biosciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Could brief Low-Oxygen breathing help hearts after spinal cord injury?
Disease control Recruiting nowThis study examines the effects of low oxygen therapy (LOT) on the stability of 24-hour blood pressure in persons with chronic cervical spinal cord injury. This study will examine if brief episodes of breathing lower oxygen, termed low oxygen therapy (LOT), which has been shown …
Phase 1/2 • Sponsor: Glen Foster • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Childhood trauma's hidden toll on MS revealed in new study
Knowledge-focused Recruiting nowThis study is structured around three main aims. In Aim 1, investigators will conduct community-based participatory research (CBPR) to develop culturally tailored methods to assess childhood adversity in multiple sclerosis (MS). Aim 2 will investigate the impact of childhood ad…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Sound waves may speed bone healing after jaw cyst surgery
Disease control Not yet recruitingThis study tested whether low-intensity pulsed ultrasound (LIPUS) could help patients recover better after surgery to remove jaw cysts. A total of 29 patients with 33 jaw cysts were included. After surgery, they were randomly assigned to two groups: Ultrasound group (17 patient…
Phase 3 • Sponsor: Sadam Elayah • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Chill out chemo pain: new device may stop nerve damage
Symptom relief Recruiting nowThis study aims to evaluate the effectiveness, tolerability, and safety of using cooling therapy and pressure (cryocompression) to reduce peripheral neuropathy, a condition affecting the nerves supplying the arms and legs (limbs) resulting in possible numbness, pain, and/or loss …
Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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No-Cuff BP monitor could revolutionize hypertension care
Disease control Recruiting nowThis multicenter, prospective, open-label randomized controlled trial evaluates the efficacy and safety of CART BP Pro-guided blood pressure management in Korean patients with uncontrolled hypertension. CART BP Pro is a wearable cuffless blood pressure monitoring device based on …
Sponsor: Korea University Anam Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Faster UTI diagnosis? DNA test takes on Old-School culture
Diagnosis Recruiting nowAdults 18 years or older with urinary tract infection (UTI) symptoms. Participants will be assigned to either the urine culture group or the DNA PCR study group by randomization. At time of enrollment in the study they will be also asked to fill out two questionnaires. If prescri…
Sponsor: University Hospitals Cleveland Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 11:01 UTC
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Body clock makeover: new study aims to tame blood sugar in seniors
Disease control OngoingIn this single arm intervention trial, the investigators will assess the impact of a personalized lifestyle plan, centered on supporting biological rhythms, on blood sugar levels, physical, cognitive and immune function in older adults with a habitual eating window of 12 hours or…
Sponsor: Salk Institute for Biological Studies • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Gene therapy hope for rare nerve disease enters first human tests
Disease control Recruiting nowThis is a phase 1b, first in-human, open-label, dose-finding study investigating the safety and tolerability of SGT-212 in participants with Friedreich's ataxia (FA). It will be delivered via dual intradentate nucleus (IDN) and intravenous (IV) administration to participants with…
Phase 1 • Sponsor: Solid Biosciences Inc. • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Mouthwash may tame chemo side effect in breast and lung cancer
Symptom relief Recruiting nowTROPION-DM/BrUOG-431 is a prospective, , phase 2 trial with two non-comparative cohorts analyzed jointly for primary endpoint in adult patients with either (Cohort 1:) advanced/metastatic hormone-receptor positive (\[HR+\], estrogen receptor and/or progesterone receptor positive)…
Phase 2 • Sponsor: Brown University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Exercise plus therapy shows promise for smoking cessation
Symptom relief Not yet recruitingSmoking remains one of the leading causes of global morbidity and mortality, responsible for more than 8 million deaths annually, according to data from the World Health Organization. In addition to its physical effects, such as cancer, cardiovascular, and respiratory diseases, t…
Sponsor: Agnaldo José Lopes • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Hand grip study aims to boost dexterity in kids with cerebral palsy
Symptom relief Recruiting nowThis Quasi experimental study investigates the effects of CHRIST on In Hand Manipulation and Grip Strength amonfg children with Spastic Cerebral Palsy. The study involves 14 children from 6-12 years of age, and will be given intervention for 10 weeks period. Key performance outc…
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Stomach bug patterns could reveal cancer risk early
Knowledge-focused Recruiting nowThis study aimed to analyze the distribution characteristics of Helicobacter pylori(H. pylori) in varying stages of atrophic gastritis and early gastric cancer using immunohistochemical staining, with the goal of providing guidance for the early screening of gastric cancer. A re…
Sponsor: Jilin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New cancer drug AK138D1 enters first human trial
Disease control Recruiting nowThis is a Phase I clinical trial testing the safety and effectiveness of AK138D1in patients with advanced cancer. The study will enroll up to 200 patients with various types of advanced solid tumors who haven't responded to standard treatments. Patients will receive AK138D1 to de…
Phase 1 • Sponsor: Akeso • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Can a broccoli compound help leukemia patients recover faster after transplant?
Disease control Recruiting nowUmbilical cord blood (UCB) is rich in haematopoietic stem progenitor cells and immune cells, and is used for transplantation for a variety of haematological disorders with the advantages of low mating requirements and fewer transplant complications. By March 2025 China's seven (e…
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Shock waves vs balloons: which best reopens clogged heart stents?
Disease control Recruiting nowPercutaneous coronary intervention (PCI) for in-stent restenosis (ISR) accounts for 5-10% of PCI. ISR may be linked to mechanical complications mainly under-expansion (UE), neointimal hyperplasia and/or neoatherosclerosis. International guidelines recommends non-compliant and ver…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Sensory play may ease autism symptoms in kids
Symptom relief Recruiting nowThe study will include 30 participants whose pre and post values will be calculated. Inclusion criteria for this study is autism spectrum disorder with the age group of 5\_11 years ,female and males both are included, those who are physically handi-capped and involved in some oth…
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New drug trial aims to tackle diabetes in cystic fibrosis patients
Disease control Recruiting nowThis study is designed to determine the pharmacokinetic and pharmacodynamic response of dorzagliatin 50 mg twice daily following 7-day administration in individuals with pancreatic insufficient cystic fibrosis and abnormal glucose tolerance when compared to randomized, double-bli…
Phase 1 • Sponsor: Michael R. Rickels, MD, MS • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC