Exercise plus therapy shows promise for smoking cessation

NCT ID NCT07186049

Not yet recruiting Symptom relief Sponsor: Agnaldo José Lopes Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a structured exercise program to cognitive-behavioral therapy (CBT) helps smokers quit more effectively than CBT alone or general health advice. Sixty-six adult smokers will be randomly assigned to one of three groups and followed for 12 weeks. Researchers will measure abstinence rates, lung function, fatigue, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise and cognitive-behavioral therapy
What this could lead to: If it works, this could point toward a more effective, drug-free way to help people quit smoking by combining physical activity with psychological support.
What could go wrong: This is a small, early-stage trial with only 66 participants, so results may not apply to everyone. The intervention is behavioral, so success depends heavily on participant motivation and adherence.

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Conditions

The condition(s) this trial relates to.

Behavior, Addictive Motor Activity nicotine dependence Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOKING (TOBACCO) ADDICTION

Contacts and locations

Locations

PPC/UERJ - Piquet Carneiro University Polyclinic

Rio de Janeiro, Rio de Janeiro, 20950-003, Brazil

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