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Sound waves may help straighten jaws in teens

NCT ID NCT07676695

Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial investigates whether adding low-intensity pulsed ultrasound to standard twin-block braces can improve jaw joint growth in teenagers with a receding lower jaw (skeletal class II malocclusion). The study involves 24 participants who will receive the combined treatment. The main goal is to measure changes in the condylar head of the jaw joint, which could lead to better facial alignment and bite correction.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low intensity pulsed ultrasound
What this could lead to
If it works, this could offer a faster, more effective way to correct jaw alignment in growing teens, potentially reducing the need for surgery later.
What could go wrong
This is a small, early-stage trial with only 24 participants, so results may not apply widely. The ultrasound device is experimental for this use, and benefits over standard treatment alone are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 14 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Skeletal class II due to retrognathic mandible. * Angle's class II Molar relationship. * All patients involved in the study were in stages II and III based on the modified cervical vertebral maturation stages (CVMS) by Bacetti et al.5 * Proclined upper incisors * Increased overjet \> 5 mm. * Aligned lower arch or average inclination * Minimal crowding of lower arch. * No history of previous orthodontic treatment. Exclusion Criteria: * Skeletal class II due to prognathic maxilla. * Patient with gross facial asymmetry. * Previous orthodontic or orthopedic treatment. * Clinical signs and symptoms of any Temporomandibular joint disorders. * Increased anterior facial vertical dimension. * Poor oral hygiene.

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Conditions

The condition(s) this trial relates to.

malocclusion due to protuberant upper front teeth Malocclusion, Angle Class II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Class II division 1 malocclusion

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Alazhar University in cairo

    RECRUITING

    Cairo, 19777, Egypt

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