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Clear aligners take on braces in overbite showdown

NCT ID NCT05684510

Disease control Sponsor: Hama University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 17, 2026 · Updated 3 times

Summary

This study tests whether clear aligners with rubber bands can correct a mild overbite (Class II malocclusion) as well as traditional braces. Twenty-four people aged 15-20 will be randomly assigned to either clear aligners or braces, both with elastics. Researchers will measure changes in jaw position and tooth alignment using X-rays.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
clear aligners with intermaxillary elastics
What this could lead to
If successful, this could show that clear aligners are as effective as braces for correcting mild overbite, offering a more comfortable and less visible treatment option.
What could go wrong
This is a small, early-stage trial with only 24 participants, so results may not apply to everyone. The study measures bone and tooth changes, not long-term stability or patient satisfaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 20 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Patients with permanent occlusion at age 15-20 years. * Patients with class II division I (half cusp or Less) with moderate overjet (2-4mm). * Patients with normal or horizontal growth pattern. * Mild crowding (\_\<2 mm) in maxillary and mandibular arch. * Patient with satisfactory periodontal health and good oral hygiene * No previous orthodontic treatment * Comprehensive medical and dental history ruling out any systemic disease. Exclusion Criteria: * Patients with periodontal disease. * Patients with vertical growth pattern. * Patients with missing or extracted teeth except third molar. * Patients with temporomandibular joint disorder. * Patients with Skeletal open bite. * Patients with poor oral and gingival health * Patients with neuromuscular disorder. * Patients with severe skeletal class II.

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Conditions

The condition(s) this trial relates to.

Malocclusion malocclusion due to protuberant upper front teeth Overbite

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Class II malocclusion Malocclusion

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hama University

    RECRUITING

    Hama, Hama Governorate, Syria

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