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Which brace fixes overbite best? new trial aims to find out

NCT ID NCT07292636

Disease control Sponsor: Aslam Alkadhimi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares two dental devices—the Twin Block and the Carriere Motion Appliance—for correcting Class II malocclusion (overbite) in teens aged 14.5 to 16. It will measure how well each device moves the teeth and jaw, and how treatment affects daily life and comfort. The goal is to help orthodontists choose the most effective and tolerable option for older adolescents.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
orthodontic appliances (Clark's Twin Block and Carriere Motion Appliance)
What this could lead to
If successful, this study could show which device works better and faster for correcting overbite in older teens, and help dentists choose the best option.
What could go wrong
This is a small, early-stage trial with only 88 participants, and results may not apply to all patients. The devices can cause discomfort and poor compliance, which may affect outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 88 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Sep 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

14 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. males and females aged 14 ½ -16 years from the HSE waiting list, 2. Cervical Vertebral Maturation (CVM) stage ≥5, 3. a mild-moderate skeletal II pattern, 4. normodivergent with average maxillomandibular planes angle (MMPA: 27±4 degrees), 5. Class II division 1 incisor relationship, 6. Class II molar relationship of ≥1/2 unit bilaterally, 7. overjet of ≥7 mm, 8. ≤5mm of dental crowding in both arches and 9. fluent English speaker. Exclusion Criteria: 1. high MMPA, 2. low MMPA, 3. have/had cleft lip or palate or craniofacial syndrome, 4. hypodontia, 5. gross mandibular asymmetry, 6. a medically diagnosed growth excess or deficiency, 7. not dentally fit or 8. had previously received orthodontic treatment.

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Conditions

The condition(s) this trial relates to.

malocclusion due to protuberant upper front teeth Malocclusion, Angle Class II Overbite

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Class II buccal segment relationship Class II division 1 malocclusion Class II growth modification Class II malocclusion Distalization GROWTH Oral health-related quality of life Overjet

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ashtown Gate HSE Orthodontic Unit

    Dublin, Dublin, D 15, Ireland

More trials for these conditions

Other studies related to the condition(s) this trial covers.