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New orthodontic wire shows promise in tiny study

NCT ID NCT07664215

Knowledge-focused Sponsor: Damascus University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested a new type of archwire designed to help move the upper front teeth backward as a group. Six adults with a specific type of overbite received the wire along with small screws and springs. The main goal was to see how fast the teeth moved and whether the wire worked as intended.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bi-dimensional archwire
What this could lead to
If this archwire works well, it could offer a more efficient way to retract front teeth during orthodontic treatment.
What could go wrong
This is a very small pilot study with only 6 participants, so results may not apply to everyone. The archwire is new and unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

6 people

The number who actually took part.

Started

Jul 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 28 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-28 years with skeletal Class II malocclusion (ANB angle 5°-7°) * Class II Division 1 dental malocclusion according to Angle classification * An average or vertical facial growth pattern * A treatment plan requiring extraction of the maxillary first premolars * A need for maxillary anterior en-masse retraction * The presence of all permanent maxillary teeth except the third molars Exclusion Criteria: * Patients with previous orthodontic treatment, * Craniofacial anomalies, systemic diseases affecting bone metabolism * Active periodontal disease * Poor oral hygiene * Missing maxillary permanent teeth, or were using * The use of medications known to influence bone metabolism

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Conditions

The condition(s) this trial relates to.

malocclusion due to protuberant upper front teeth Malocclusion, Angle Class II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Class II division 1 malocclusion Malocclusion class II

Contacts and locations

Locations

  • Department of Orthodontics, Faculty of Dentistry, University of Damascus

    Damascus, DM20AM19, Syria

More trials for these conditions

Other studies related to the condition(s) this trial covers.