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New stents tested in thousands of heart patients

NCT ID NCT05044273

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is tracking 2,000 people with coronary artery disease who receive either a Synergy XD or Synergy Megatron stent during a routine procedure to open blocked heart arteries. Researchers want to see how these stents perform in everyday medical practice compared to other drug-eluting stents. The main goal is to measure the rate of death, heart attack, or need for another procedure over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Synergy XD stent and Synergy Megatron stent (drug-eluting stents)
What this could lead to
If successful, this could show that these stents are a safe and effective option for opening blocked heart arteries in everyday practice.
What could go wrong
This is an observational study, not a controlled trial, so results may be less definitive. Stents carry risks like blood clots or re-narrowing of the artery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2022

Expected to finish

Dec 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with Synergy XD stent or Synergy Megatron™ stent

Ages

19 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients ≥ 19 years old * Patients receiving Synergy XD stent(s) or Synergy Megatron™ stent(s). * The patient or guardian agrees to the study protocol and the schedule of clinical follow-up and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethics Committee of the respective clinical site. Exclusion Criteria: * Patients with a mixture of other drug-eluting stents (DESs) * Terminal illness with life-expectancy ≤1 year. * Patients with cardiogenic shock

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    19 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, South Korea

  • CHA Bundang Medical Center, CHA University

    TERMINATED

    Seongnam, South Korea

  • Chonnam National University Hospital

    RECRUITING

    Gwangju, South Korea

  • Dong-A University Hospital

    RECRUITING

    Busan, South Korea

  • Gangneung Asan Hospital

    RECRUITING

    Gangneung, South Korea

  • Gyeongsang National University Changwon Hospital

    RECRUITING

    Changwon, South Korea

  • Hallym University Medical Center

    RECRUITING

    Anyang, South Korea

  • Hanyang University Seoul Hospital

    RECRUITING

    Seoul, South Korea

  • Inje University Busan Paik Hospital

    TERMINATED

    Busan, South Korea

  • Inje university Pusan Paik hospital

    RECRUITING

    Busan, South Korea

  • Keimyung University Dongsan Medical Center

    RECRUITING

    Daegu, South Korea

  • Korea University Anam Hospital

    RECRUITING

    Seoul, South Korea

  • Korea University Guro Hospital

    TERMINATED

    Seoul, South Korea

  • Pusan National University Hospital

    TERMINATED

    Busan, South Korea

  • Pusan National University Hospital

    RECRUITING

    Busan, South Korea

  • Pusan National University Yangsan Hospital

    RECRUITING

    Busan, South Korea

  • Samsung Changwon Hospital

    RECRUITING

    Changwon, South Korea

  • Seoul university Bundang hospital

    RECRUITING

    Seongnam, South Korea

  • The Catholic University of Korea, ST. Vincent's Hospital

    RECRUITING

    Suwon, South Korea

  • Ulsan University Hospital

    RECRUITING

    Ulsan, South Korea

  • Veterans Hospital

    RECRUITING

    Daegu, South Korea

  • Wonkwang University Hospital

    RECRUITING

    Iksan, South Korea

  • Yeungnam University Medical Center

    RECRUITING

    Daegu, South Korea

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