New stents tested in thousands of heart patients
NCT ID NCT05044273
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is tracking 2,000 people with coronary artery disease who receive either a Synergy XD or Synergy Megatron stent during a routine procedure to open blocked heart arteries. Researchers want to see how these stents perform in everyday medical practice compared to other drug-eluting stents. The main goal is to measure the rate of death, heart attack, or need for another procedure over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Synergy XD stent and Synergy Megatron stent (drug-eluting stents)
- What this could lead to
- If successful, this could show that these stents are a safe and effective option for opening blocked heart arteries in everyday practice.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be less definitive. Stents carry risks like blood clots or re-narrowing of the artery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 2,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2022
- Expected to finish
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Dec 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with Synergy XD stent or Synergy Megatron™ stent
- Ages
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19 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients ≥ 19 years old * Patients receiving Synergy XD stent(s) or Synergy Megatron™ stent(s). * The patient or guardian agrees to the study protocol and the schedule of clinical follow-up and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethics Committee of the respective clinical site. Exclusion Criteria: * Patients with a mixture of other drug-eluting stents (DESs) * Terminal illness with life-expectancy ≤1 year. * Patients with cardiogenic shock
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
19 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Asan Medical Center
RECRUITINGSeoul, South Korea
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CHA Bundang Medical Center, CHA University
TERMINATEDSeongnam, South Korea
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Chonnam National University Hospital
RECRUITINGGwangju, South Korea
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Dong-A University Hospital
RECRUITINGBusan, South Korea
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Gangneung Asan Hospital
RECRUITINGGangneung, South Korea
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Gyeongsang National University Changwon Hospital
RECRUITINGChangwon, South Korea
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Hallym University Medical Center
RECRUITINGAnyang, South Korea
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Hanyang University Seoul Hospital
RECRUITINGSeoul, South Korea
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Inje University Busan Paik Hospital
TERMINATEDBusan, South Korea
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Inje university Pusan Paik hospital
RECRUITINGBusan, South Korea
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Keimyung University Dongsan Medical Center
RECRUITINGDaegu, South Korea
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Korea University Anam Hospital
RECRUITINGSeoul, South Korea
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Korea University Guro Hospital
TERMINATEDSeoul, South Korea
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Pusan National University Hospital
TERMINATEDBusan, South Korea
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Pusan National University Hospital
RECRUITINGBusan, South Korea
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Pusan National University Yangsan Hospital
RECRUITINGBusan, South Korea
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Samsung Changwon Hospital
RECRUITINGChangwon, South Korea
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Seoul university Bundang hospital
RECRUITINGSeongnam, South Korea
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The Catholic University of Korea, ST. Vincent's Hospital
RECRUITINGSuwon, South Korea
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Ulsan University Hospital
RECRUITINGUlsan, South Korea
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Veterans Hospital
RECRUITINGDaegu, South Korea
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Wonkwang University Hospital
RECRUITINGIksan, South Korea
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Yeungnam University Medical Center
RECRUITINGDaegu, South Korea
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