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Can oxygen drops during seizures predict sudden death in epilepsy?

NCT ID NCT02572297

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study enrolled over 1,000 people with drug-resistant partial epilepsy to see if severe drops in oxygen levels during seizures can predict later sudden unexpected death (SUDEP). Participants had their seizures recorded with video-EEG monitoring. The goal is to better understand risk factors and potentially prevent these tragic deaths.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help identify patients at higher risk for SUDEP and point toward ways to prevent it.
What could go wrong
This is an observational study, not a treatment trial. It may not find a clear link, and results may not lead to immediate prevention strategies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,072 people

The number who actually took part.

Started

May 2010

Finished

Aug 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients suffering from drud-resistant partial epilepsy whom a video-EEG monitoring of their seizures was scheduled as part of a pre-surgical assessment

Ages

15 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients suffering from drud-resistant partial epilepsy ; * Patients who are at least 15 years ; * Patients for whom a video-EEG monitoring of their seizures was scheduled as part of a pre-surgical assessment ; * Patients having a registration number in the RNIP (Répertoire National d'Identification des Personnes Physiques) or a Social Security number * Patients who have given their written consent ; * Patients with a social security Exclusion Criteria: * Patients under 15 years * Patients without drug-resistant partial epilepsy * Patients without a registration number in the RNIP (Répertoire National d'Identification des Personnes Physiques) or a Social Security number) * Patient without a consent signed

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Conditions

The condition(s) this trial relates to.

epilepsy focal epilepsy Sudden Unexpected Death in Epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Drug-resistant partial epilepsy

Contacts and locations

Locations

  • Service de Neurologie Fonctionnelle et d'Epileptologie, Hôpital Pierre Wertheimer, Hospices Civils de Lyon

    Bron, 69677, France

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