New MRI technique may spot seizure origins without needles or incisions
NCT ID NCT02304029
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a special type of MRI that measures sodium levels in the brain can help locate the exact area causing seizures in people with drug-resistant epilepsy. 78 patients who were already scheduled for epilepsy surgery received a sodium MRI scan. Researchers compared the scan results to the actual surgical site and to patients' outcomes after surgery. The goal was to see if this non-invasive method could replace or reduce the need for invasive brain electrode recordings.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could provide a non-invasive way to pinpoint where seizures start, helping guide surgery and possibly reducing the need for invasive brain recordings.
- What could go wrong
- This is a small, completed study (78 people) testing a new imaging technique. It may not be accurate enough to replace current methods, and results need confirmation in larger trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
78 people
The number who actually took part.
- Started
-
Mar 2015
- Finished
-
Nov 2019
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient presenting a drug-resistant partial epilepsy for which an indication is indicated after préchirugical balance assessment. * Patient not presenting a psychiatric disease chronicles, an demential syndrome, * Patient not presenting contraindication to the realization of an examination by MRI Exclusion Criteria: * Patient suffering a not operable shape of partial epilepsy or a generalized epilepsy * Patient suffering an evolutionary associated serious illness (cancer, autoimmune disease, hepatic insufficiency)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Drug-resistant partial epilepsy are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Assistance Publique - Hopitaux de Marseille
Marseille, 13005, France
-
CHU Montpellier
Montpellier, France
-
CHU NICE
Nice, France
-
CHU Nimes
Nîmes, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Researchers dig into thousands of medical records to unlock secrets of prolonged seizures
- Brain-Scan showdown: which test best finds seizure hotspots?
- New brain electrodes aim to pinpoint seizure origins
- Can oxygen drops during seizures predict sudden death in epilepsy?
- New brain scanner could sharpen epilepsy surgery targeting
- Glasses that see seizures coming: new wearable aims to predict epilepsy attacks