New bracelet calms Parkinson's tremors in small trial
NCT ID NCT06886178
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a special brace (STIL Orthosis) designed to reduce shaking (tremor) in people with Parkinson's disease. 25 participants had their tremor measured while wearing the active brace, a fake brace, and no brace. The goal was to see if the device could make everyday tasks easier and if people found it comfortable to use.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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25 people
The number who actually took part.
- Started
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Feb 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participant is at least 18 years of age. * Willing to sign the informed consent. * Diagnosed with Parkinson's disease by a neurologist or movement disorders specialist. * Action tremor in one or two arms (clinical severity score of at least 2 on their dominant side, on MDS-UPDRS items 3.15 or 3.16). * At least experiencing wrist flexion/extension or forearm pronation/supination tremor. Exclusion Criteria: * Diagnosed with any other neurological disorder, such as epilepsy, Essential tremor, functional tremor, physiologic tremor, cerebellar tremor, MS, spasticity, ataxia, dystonia, Alzheimer's disease or dementia, atypical parkinsonism, peripheral neuropathy affecting the arms (e.g., carpal tunnel syndrome). * Disease duration of \> 15 years. * Experiencing severe bradykinesia/rigidity, to such an extent that the participant is unable to perform the ADL tasks (drinking, eating, pouring water). * Limited movement or muscle function in the arm/hand (for contractures or muscle diseases), or loss of muscle function in one arm (e.g., due to paralysis, or amputation). * Swollen, infected, inflamed areas, or skin eruptions, open wounds, or cancerous lesions of skin on the forearm or hand that would wear the orthosis during the clinical investigation. * Consuming excessive alcohol (more than 21 glasses per week for men and 14 glasses per week for women), as defined in the GGZ guidelines on alcohol use. * Having received a botulinum toxin injection to suppress hand tremor in the past six months, or planned in the coming 60 days. * Previous or planned Deep Brain Stimulation (DBS) at time of study enrollment that interferes with testing. * Change in any tremor medication in the past 30 days or planned during the period of testing. * A hand circumference smaller than 170 mm, or larger than 250 mm. * An upper arm circumference smaller than 180 mm, or larger than 350 mm. * Patch/band-aid allergies. * Participant is unable to communicate with the investigator and staff due to: (1) not mastering the Dutch and English language, (2) blindness, (3) deafness, (4) illiteracy. * Pregnancy or anticipated pregnancy at time of study enrollment. * Any health condition that in the neurologist's opinion should preclude participation in this study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Donders Institute for Brain, Cognition and Behaviour
Nijmegen, Gelderland, 6511EN, Netherlands
More trials for these conditions
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