Shaking off stigma: brain procedure may ease social burden of hand tremors
NCT ID NCT07430761
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a brain treatment called focused ultrasound can reduce the social stigma that people with essential tremor often face. About 220 adults with essential tremor will have their tremor treated and then be followed for one year. Researchers want to see if less shaking leads to less embarrassment, anxiety, and avoidance of social situations.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 220 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2025
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who are scheduled to undergo stereotactic thalamotomy guided by four-tract tractography at the University of Texas Southwestern Medical Center for the treatment of Essential Tremor (ET). As is standard of practice, the diagnosis of ET and the judgment that this procedure is medically necessary will have been made by a movement disorder specialist. Once the procedure is scheduled, patients are invited to participate in this observational prospective study of effects on ET stigma.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * People with ET as diagnosed by a movement disorder neurologist * Tremor of sufficient severity and impact on quality of life so as to justify a lesional brain procedure * Competent to consent to undergoing high intensity focused ultrasound thalamotomy targeted by 4-tract tractography * Provide verbal informed consent to this study of ET stigma Exclusion Criteria: * Patient declines to participate in this observational study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Texas Soouthwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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