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New drug combo tested for tough cancers

NCT ID NCT04234113

First seen Apr 05, 2026 · Last updated Jun 15, 2026 · Updated 12 times

Summary

This early-stage study tested a new drug called SO-C101, either alone or with another drug (pembrolizumab), in 115 people with advanced solid tumors like lung, kidney, or skin cancer. The main goal was to see if the treatment was safe and to look for early signs of tumor shrinkage. The study was stopped early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Léon Bérard

    Lyon, France, 69379, France

  • Hopital Saint Louis

    Paris, 75010, France

  • Hôpitaux Universitaires de Marseille Timone

    Marseille, 13005, France

  • Institut Claudius Regaud

    Toulouse, France, 31059, France

  • Institut Gustave Roussy

    Paris, France, 94805, France

  • Institut de Cancerologie de L'Ouest

    Saint-Herblain, 44805, France

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Masarykův Onkologický Ústav Brno Klinika komplexní onkologické péče

    Brno, Czechia, 65653, Czechia

  • University Hospital Sanchinarro

    Madrid, 28050, Spain

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15216, United States

  • Vall d'Hebron Institute of Oncology

    Barcelona, Spain, 08035, Spain

  • Yale Cancer Center

    New Haven, Connecticut, 06520, United States

Conditions

The condition(s) this trial relates to.

anus neoplasm Biliary Tract Neoplasms cutaneous neuroendocrine carcinoma gastric neoplasm hepatocellular carcinoma melanoma mesothelioma non-small cell lung carcinoma ovarian cancer renal cell carcinoma small cell lung carcinoma Squamous Cell Carcinoma of Head and Neck Thymus Neoplasms Thyroid Neoplasms triple-negative breast carcinoma Urinary Bladder Neoplasms Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.