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Could poor sleep before surgery cloud your mind after? new study investigates

NCT ID NCT07392840

Knowledge-focused Sponsor: Minia University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether sleep problems before surgery and a brain chemical called melanin-concentrating hormone (MCH) are linked to delayed mental recovery in adults aged 65 and older after spinal anesthesia. Researchers will measure MCH in spinal fluid and blood, and compare patients with and without sleep issues. The goal is to better understand who might be at risk for confusion or memory problems after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help identify older adults at risk for mental confusion after surgery, leading to better pre-surgery care.
What could go wrong
This is a small, early observational study (50 people) that only looks for links—it does not test any treatment. Results may not apply to all older adults.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

A total of (50) patients candidate for elective lower limb surgery aged from 65 years of both sexes will be enrolled in this study.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients of both genders ageing 65 years or above. * ASA grade I to III. * Undergo elective lower limb surgery under spinal anesthesia * Agree to collect one's own CSF and blood samples Exclusion Criteria: * Past history of depression,anxiety,delirium and schizophrenia . * Past history of drug dependence. * Past history of dementia,including Alzheimer disease(AD). * Preoperative Montreal Cognitive Assessment (MoCA) score \<26. * Inability to understand or cooperate with the evaluation scale or questionnaire. * Refuse collecting one's own CSF and blood samples.

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Conditions

The condition(s) this trial relates to.

Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative cognitive dysfunction

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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